Thibault Varin
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Explore the profile of Thibault Varin including associated specialties, affiliations and a list of published articles.
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19
Citations
233
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Recent Articles
1.
Ouamba A, Gagnon M, Varin T, Chouinard P, LaPointe G, Roy D
Front Microbiol
. 2023 Nov;
14:1175663.
PMID: 38029116
Introduction: The microbiota of bulk tank raw milk is known to be closely related to that of microbial niches of the on-farm environment. Preserved forage types are partof this ecosystem...
2.
Renaud V, Faucher M, Dubois M, Pilon G, Varin T, Marette A, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37629151
The development of Metabolic Syndrome (MetS) affects a large number of people around the world and represents a major issue in the field of health. Thus, it is important to...
3.
Valle M, Mitchell P, Pilon G, Varin T, Henault L, Rolin J, et al.
Obesity (Silver Spring)
. 2021 Aug;
29(10):1635-1649.
PMID: 34449134
Objective: This study investigated the effects of a low-dose salmon peptide fraction (SPF) and vitamin D (VitD ) in obese and VitD -deficient mice at risk of metabolic syndrome (MetS)....
4.
Valle M, Mitchell P, Pilon G, St-Pierre P, Varin T, Richard D, et al.
J Nutr
. 2021 Apr;
151(5):1175-1189.
PMID: 33851198
Background: Cholecalciferol (D3) may improve inflammation, and thus provide protection from cardiometabolic diseases (CMD), although controversy remains. Omega-3 fatty acids (ω-3FA) may also prevent the development of CMD, but the...
5.
Rodriguez-Daza M, Daoust L, Boutkrabt L, Pilon G, Varin T, Dudonne S, et al.
Sci Rep
. 2020 Feb;
10(1):2217.
PMID: 32041991
Blueberries are a rich source of polyphenols, widely studied for the prevention or attenuation of metabolic diseases. However, the health contribution and mechanisms of action of polyphenols depend on their...
6.
Wang J, Varin T, Vieth M, Elkins J
Open Biol
. 2019 Apr;
9(4):190037.
PMID: 30991936
The RIO kinases (RIOKs) are a universal family of atypical kinases that are essential for assembly of the pre-40S ribosome complex. Here, we present the crystal structure of human RIO...
7.
Denis M, Roy D, Yeganeh P, Desjardins Y, Varin T, Haddad N, et al.
Clin Sci (Lond)
. 2016 Sep;
130(23):2217-2237.
PMID: 27630205
Diets rich in fruits and vegetables may reduce oxidative stress (OxS) and inflammation via several mechanisms. These beneficial effects may be due to their high polyphenol content. The aims of...
8.
Schuffenhauer A, Varin T
Mol Inform
. 2016 Jul;
30(8):646-64.
PMID: 27467257
Databases for small organic chemical molecules usually contain millions of structures. The screening decks of pharmaceutical companies contain more than a million of structures. Nevertheless chemical substructure searching in these...
9.
Varin T, Godfrey A, Masquelin T, Nicolaou C, Evans D, Vieth M
Biochim Biophys Acta
. 2015 Apr;
1854(10 Pt B):1630-6.
PMID: 25891899
We report the discovery and initial optimization of diphenpyramide and several of its analogs as hRIO2 kinase ligands. One of these analogs is the most selective hRIO2 ligand reported to...
10.
Martin E, Knapp S, Engh R, Moebitz H, Varin T, Roux B, et al.
Biochim Biophys Acta
. 2015 Apr;
1854(10 Pt B):1595-604.
PMID: 25861861
Recent advances in understanding the activity and selectivity of kinase inhibitors and their relationships to protein structure are presented. Conformational selection in kinases is studied from empirical, data-driven and simulation...