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Thibault Troadec

Explore the profile of Thibault Troadec including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 45
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Recent Articles
1.
Marlin A, Le Pape F, Troadec T, Le Goff J, Tripier R, Berthou C, et al.
Dalton Trans . 2025 Feb; 54(9):3939-3951. PMID: 39895421
Three macrocyclic tacn (1,4,7-triazacyclononane) derivatives containing one, two and three 2-methylpyridine pendant arms (no1py, no2py and no3py), compared to the linear diamine analogue tpen (,,','-tetrakis(2-methylpyridinyl)-ethylenediamine) known for its capacity to...
2.
Le Roy M, Metivier C, Rbah-Vidal L, Saec P, Bouhsine H, Cherel M, et al.
Bioorg Med Chem Lett . 2024 Nov; 115:130027. PMID: 39551220
Thank to their particular pharmacokinetics, the use of small organic molecules can be a very promising alternative to macromolecular targeting biomolecules (i.e. antibodies, peptides…) for specific imaging of tumours. Herein,...
3.
Sire C, Meneyrol V, Saffon-Merceron N, Terreno E, Garello F, Tei L, et al.
Chem Sci . 2024 Aug; 15(33):13550-13557. PMID: 39183922
Macrocyclic chelators play a central role in medical imaging and nuclear medicine owing to their unparalleled metal cation coordination abilities. Their functionalization by fluorinated groups is an attractive design, to...
4.
Le Roy M, Claes S, Saffon-Merceron N, Schols D, Troadec T, Tripier R
Org Biomol Chem . 2024 Mar; 22(15):3059-3067. PMID: 38545887
This article presents the controlled synthesis of a rare example of ,'-linked bis-cyclam architecture in mild conditions through the "bis-aminal" route previously used for the advantageous synthesis of cyclam, -...
5.
Le Roy M, Hery S, Saffon-Merceron N, Platas-Iglesias C, Troadec T, Tripier R
Inorg Chem . 2023 May; 62(21):8112-8122. PMID: 37191969
Although cyclam-based ligands are among the strongest copper(II) chelators available, they also usually present good affinity for other divalent cations [Zn(II), Ni(II), and Co(II)], with no copper(II)-specific cyclam ligands having...
6.
Takahashi S, Nougue R, Troadec T, Baceiredo A, Saffon-Merceron N, Branchadell V, et al.
Inorg Chem . 2023 Apr; 62(16):6488-6498. PMID: 37043365
A base-stabilized -phosphonio--amino-silyne was synthesized, using an original method, through a coupling reaction between two Lewis-base-stabilized low-valent species: a silyliumylidene ion and a P,S-bis-ylide [C(0)-complex]. This new isolable cationic silyne...
7.
Marlin A, Le Pape F, Le Goff J, Hamon N, Troadec T, Tripier R, et al.
Bioconjug Chem . 2022 Jun; 33(7):1377-1392. PMID: 35709513
The 1,4,7-tris-(2-pyridinylmethyl)-1,4,7-triazacyclononane ligand () and its bifunctional analogue were synthesized to investigate their action toward zinc(II) depletion related to the apoptosis phenomenon in chronic lymphocytic leukemia (CLL) cells. was used...
8.
Knighton R, Troadec T, Mazan V, Saec P, Marionneau-Lambot S, Le Bihan T, et al.
Inorg Chem . 2021 Jan; 60(4):2634-2648. PMID: 33496592
Herein we present the preparation of two novel cyclam-based macrocycles ( and ), bearing phosphonate-appended pyridine side arms for the coordination of copper(II) ions in the context of Cu PET...
9.
Knighton R, Soro L, Troadec T, Mazan V, Nonat A, Elhabiri M, et al.
Inorg Chem . 2020 Jul; 59(14):10311-10327. PMID: 32639724
Ligands and , respectively based on a cyclam and a cross-bridged cyclam scaffold functionalized at N1 and N8 by 6-phosphonic-2-methylene pyridyl groups, are described. While complexation of lanthanide (Ln) cations...
10.
Bordes A, Poveda A, Troadec T, Franconetti A, Arda A, Perrin F, et al.
Org Lett . 2020 Mar; 22(6):2344-2349. PMID: 32153195
A new family of chiral symmetric tetraazamacrocycles, coined ISAC for IminoSugar Aza-Crown, incorporating two iminosugars adopting a C conformation is disclosed. Multinuclear NMR experiments on the corresponding Cd complex show...