Thibaud Spinetti
Overview
Explore the profile of Thibaud Spinetti including associated specialties, affiliations and a list of published articles.
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19
Citations
880
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Recent Articles
1.
Gebhard C, Sutsch C, Gebert P, Gysi B, Bengs S, Todorov A, et al.
Euro Surveill
. 2024 Jan;
29(2).
PMID: 38214079
BackgroundWomen are overrepresented among individuals with post-acute sequelae of SARS-CoV-2 infection (PASC). Biological (sex) as well as sociocultural (gender) differences between women and men might account for this imbalance, yet...
2.
Deforth M, Gebhard C, Bengs S, Buehler P, Schuepbach R, Zinkernagel A, et al.
Diagn Progn Res
. 2022 Nov;
6(1):22.
PMID: 36384641
Background: The coronavirus disease 2019 (COVID-19) pandemic demands reliable prognostic models for estimating the risk of long COVID. We developed and validated a prediction model to estimate the probability of...
3.
Akbil B, Meyer T, Stubbemann P, Thibeault C, Staudacher O, Niemeyer D, et al.
J Clin Immunol
. 2022 May;
42(6):1111-1129.
PMID: 35511314
Purpose: Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early identification of IFN-AAB-positive patients...
4.
Lerch S, Schefold J, Spinetti T
Pharmacology
. 2022 Apr;
107(7-8):359-367.
PMID: 35413710
Background: The enzyme indolamine-2,3-dioxygenase 1 (IDO1) is the rate-limiting enzyme of the kynurenine (KYN) pathway and metabolizes the essential amino acid tryptophan to KYNs. The depletion of tryptophan and the...
5.
Hirzel C, Grandgirard D, Surial B, Wider M, Leppert D, Kuhle J, et al.
Ther Adv Neurol Disord
. 2022 Mar;
15:17562864221080528.
PMID: 35299779
Background: In coronavirus disease-2019 (COVID-19) patients, there is increasing evidence of neuronal injury by the means of elevated serum neurofilament light chain (sNfL) levels. However, the role of systemic inflammation...
6.
Bombaci G, Sarangdhar M, Andina N, Tardivel A, Yu E, Mackie G, et al.
Life Sci Alliance
. 2022 Mar;
5(6).
PMID: 35256513
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1-mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory diseases and...
7.
Pfortmueller C, Spinetti T, Urman R, Luedi M, Schefold J
Best Pract Res Clin Anaesthesiol
. 2021 Sep;
35(3):351-368.
PMID: 34511224
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two SARS-CoV-2 pandemic "waves," intensive care unit (ICU) specialists are treating a...
8.
Spagnuolo L, Puddinu V, Boss N, Spinetti T, Oberson A, Widmer J, et al.
Eur J Immunol
. 2021 Jun;
51(8):1980-1991.
PMID: 34060652
High mobility group box-1 protein (HMGB1) is an alarmin that, once released, promotes inflammatory responses, alone and as a complex with the chemokine CXCL12. Here, we report that the HMGB1-CXCL12...
9.
Osuchowski M, Winkler M, Skirecki T, Cajander S, Shankar-Hari M, Lachmann G, et al.
Lancet Respir Med
. 2021 May;
9(6):622-642.
PMID: 33965003
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with devastating consequences. While the medical community has gained insight into the epidemiology of COVID-19, important questions remain about...
10.
Winkler M, Skirecki T, Brunkhorst F, Cajander S, Cavaillon J, Ferrer R, et al.
EBioMedicine
. 2021 Apr;
66:103291.
PMID: 33813139
Many milestones in medical history rest on animal modeling of human diseases. The SARS-CoV-2 pandemic has evoked a tremendous investigative effort primarily centered on clinical studies. However, several animal SARS-CoV-2/COVID-19...