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Thessa Laeremans

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Articles 9
Citations 65
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Recent Articles
1.
Laeremans T, Janssens A, Aerts J
Immunotherapy . 2025 Feb; 17(2):133-145. PMID: 39905963
Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells both play essential roles in controlling viral infections by eliminating virus-infected cells. Unlike CTLs, which require priming and activation by antigen-presenting...
2.
Dhaese S, den Roover S, Verbeke R, Aernout I, Meulewater S, Cosyns J, et al.
Mol Ther Nucleic Acids . 2024 Dec; 35(4):102372. PMID: 39618822
mRNA nanoparticles have been investigated in the context of prophylactic vaccination against HIV, but their effectivity has not been widely investigated in therapeutic vaccination. It has been suggested that a...
3.
Schober R, Brandus B, Laeremans T, Iserentant G, Rolin C, Dessilly G, et al.
J Transl Med . 2023 Nov; 21(1):791. PMID: 37936122
Background: Combination antiretroviral therapy (cART) has dramatically extended the life expectancy of people living with HIV-1 and improved their quality of life. There is nevertheless no cure for HIV-1 infection...
4.
Ramaut L, Moonen L, Laeremans T, Aerts J, Geeroms M, Hamdi M
Aesthet Surg J . 2023 May; 43(9):NP696-NP703. PMID: 37130047
Background: Mechanical isolation of the stromal vascular fraction (SVF) separates the stromal component from the parenchymal cells. Emulsification is currently the most commonly used disaggregation method and is effective in...
5.
Laeremans T, den Roover S, Lungu C, Dhaese S, Gruters R, Allard S, et al.
NPJ Vaccines . 2023 Mar; 8(1):29. PMID: 36864042
Although natural killer (NK) cells have been studied in connection with dendritic cell (DC)-based vaccination in the field of cancer immunology, their role has barely been addressed in the context...
6.
Laeremans T, Dhaese S, Aernout J, Barbe K, Pannus P, Rutsaert S, et al.
AIDS . 2022 Sep; 36(13):1761-1768. PMID: 36172869
Objectives: Suppression of viral replication in patients on antiretroviral therapy (ART) is determined by plasma viral load (pVL) measurement. Whenever pVL reaches values below the limit of quantification, the qualitative...
7.
Dhaese S, Laeremans T, den Roover S, Allard S, Vanham G, Aerts J
Pharmaceutics . 2022 Jul; 14(7). PMID: 35890284
A major determinant for the success of mRNA-based vaccines is the composition of the nanoparticles (NPs) used for formulation and delivery. Cationic peptides represent interesting candidate carriers for mRNA, since...
8.
Kalus P, De Munck J, Vanbellingen S, Carreer L, Laeremans T, Broos K, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563257
Recently, a paradigm shift has been established for oncolytic viruses (OVs) as it was shown that the immune system plays an important role in the specific killing of tumor cells...
9.
Vancamelbeke M, Laeremans T, Vanhove W, Arnauts K, Santo Ramalho A, Farre R, et al.
J Crohns Colitis . 2019 Mar; 13(10):1351-1361. PMID: 30919886
Background And Aims: In vitro studies using immortalised cancer cell lines showed that butyrate has an overall positive effect on epithelial barrier integrity, but the physiological relevance of cancer cell...
10.
Veltman D, Laeremans T, Passante E, Huber H
J Theor Biol . 2016 Dec; 415:125-136. PMID: 28017802
Activation of the NLRP3-inflammasome pathway and production of the inflammatory cytokine IL-1B after cellular damage caused by infarct or infection is a key process in several diseases such as acute...