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Thereza Quirico-Santos

Explore the profile of Thereza Quirico-Santos including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 524
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Recent Articles
1.
Gama J, Romualdo R, de Assis M, de Oliveira L, Quirico-Santos T, Alves L, et al.
Biomolecules . 2022 Jun; 12(6). PMID: 35740942
Muscle injuries are frequent in individuals with genetic myopathies and in athletes. Skeletal muscle regeneration depends on the activation and differentiation of satellite cells present in the basal lamina of...
2.
Gaglianone R, Bloise F, Lagrota-Candido J, Mermelstein C, Quirico-Santos T
Histol Histopathol . 2021 Apr; 36(7):775-783. PMID: 33825181
The mdx mouse model of Duchenne Muscular Dystrophy (DMD) presents sarcolemma instability and develops a mild multi-stage dystrophinopathy characterized by intense myonecrosis with inflammatory infiltrate at 4-weeks; muscular regeneration at...
3.
Santos J, Faria G, Cruz W, Fontes C, Schonthal A, Quirico-Santos T, et al.
Surg Neurol Int . 2020 Dec; 11:389. PMID: 33282452
Background: Standard of care for glioblastoma (GB), consisting of cytotoxic chemotherapy, steroids, and high-dose radiation, induces changes in the tumor microenvironment through its effects on glucose availability, which is a...
4.
Gama J, Pinheiro D, da Silva R, Quirico-Santos T, Lagrota-Candido J
Cell Tissue Res . 2020 Jul; 382(3):447-455. PMID: 32661578
Although the primary cause of Duchenne muscular dystrophy (DMD) is a genetic mutation, the inflammatory response contributes directly to severity and exacerbation of the diaphragm muscle pathology. The omentum is...
5.
Medeiros T, Saraiva G, Moraes L, Gomes A, Lacerda G, Leite P, et al.
Dig Liver Dis . 2020 Jun; 52(10):1170-1177. PMID: 32522433
Background And Aims: Disturbances in matrix metalloproteinases (MMPs) and corresponding tissue inhibitors (TIMPs) contribute to hepatitis C virus (HCV)-induced fibrosis. This study aimed to determine MMP-9/TIMP-1 levels in addition to...
6.
Faria G, Soares I, Salazar M, Amorim M, Pessoa B, da Fonseca C, et al.
BMC Cancer . 2020 Apr; 20(1):294. PMID: 32264844
Background: Polymorphisms in MTHFR gene influence risk and overall survival of patients with brain tumor. Global genomic DNA (gDNA) methylation profile from tumor tissues is replicated in peripheral leukocytes. This...
7.
Gaglianone R, Bloise F, Ortiga-Carvalho T, Quirico-Santos T, Costa M, Mermelstein C
Histol Histopathol . 2019 Jul; 35(2):203-216. PMID: 31274171
Sarcolemma instability and increased calcium influx in muscle fibers are characteristics of the Duchenne muscular dystrophy. Excessive calcium activates calcium-dependent enzymes, such as calpains (CAPN) and matrix metalloproteases (MMP). Here,...
8.
Mello C, Quirico-Santos T, Amorim L, Silva V, Fragel L, Bloom D, et al.
Antivir Ther . 2019 May; 25(1):1-11. PMID: 31099756
Background: Infection by herpes simplex type-1 virus (HSV-1) causes several pathological processes, including cutaneous, oral and genital infections, fatal encephalitis and cognitive dysfunction due to grey matter loss. Acyclovir is...
9.
Pinheiro D, da Silva R, Barbosa T, Gama J, Gomes A, Quirico-Santos T, et al.
Cell Tissue Res . 2019 Apr; 377(2):269-279. PMID: 30953145
Duchenne muscular dystrophy is a lethal X-linked muscle wasting disease due to mutations of the dystrophin gene leading to distinct susceptibility to degeneration and fibrosis among skeletal muscles. This study...
10.
Gaglianone R, Teixeira Santos A, Bloise F, Ortiga-Carvalho T, Costa M, Quirico-Santos T, et al.
Sci Rep . 2019 Feb; 9(1):1986. PMID: 30760802
Mitochondria play an important role in providing ATP for muscle contraction. Muscle physiology is compromised in Duchenne muscular dystrophy (DMD) and several studies have shown the involvement of bioenergetics. In...