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Thereza Quirico-Santos

Explore the profile of Thereza Quirico-Santos including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 524
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Recent Articles
11.
Faria G, Silva E, Da Fonseca C, Quirico-Santos T
Int J Mol Sci . 2018 Jun; 19(6). PMID: 29848970
Tumor infiltration into brain tissue usually remains undetected even by high-resolution imaging. Molecular markers are used to increase diagnostic accuracy, but with limited continuous monitoring application. We evaluated the potential...
12.
Santos J, Da Cruz W, Schonthal A, Salazar M, Fontes C, Quirico-Santos T, et al.
Oncol Lett . 2018 Feb; 15(1):1263-1270. PMID: 29391903
It has been hypothesized that persistent ketotic hypoglycemia represents a potential therapeutic strategy against high-grade gliomas. Perillyl alcohol (POH) is a non-toxic, naturally-occurring, hydroxylated monoterpene that exhibits cytotoxicity against temozolomide-resistant...
13.
Gomes A, Mello A, Ribeiro M, Garcia D, da Fonseca C, Salazar M, et al.
Arch Immunol Ther Exp (Warsz) . 2017 Mar; 65(4):285-297. PMID: 28314870
Monoterpenes such as limonene and perillyl alcohol (POH) are promising natural compounds with pro-oxidant properties partly due to endoplasmic reticulum (ER) stress-induced cytotoxicity, and antioxidant activity owing to their activity...
14.
Paiva-Oliveira E, da Silva R, Bellio M, Quirico-Santos T, Lagrota-Candido J
Histochem Cell Biol . 2017 Mar; 148(1):49-60. PMID: 28293722
Tissue damage triggers innate immune response mediated by Toll-like receptor 4 (TLR) that recognizes endogenous host danger molecules associated with cell death and tissue inflammation, although the precise role of...
15.
da Fonseca C, Khandelia H, Salazar M, Schonthal A, Meireles O, Quirico-Santos T
Surg Neurol Int . 2016 Feb; 7:1. PMID: 26862440
Background: Gliomas display a high degree of intratumor heterogeneity, including changes in physiological parameters and lipid composition of the plasma membrane, which may contribute to the development of drug resistance....
16.
Leite P, Gandia L, de Pascual R, Nanclares C, Colmena I, Santos W, et al.
Brain Res . 2014 May; 1573:27-36. PMID: 24833065
Amount evidence indicates that α7 nicotinic acetylcholine receptor (nAChRα7) activation reduces production of inflammatory mediators. This work aimed to verify the influence of endogenous nAChRα7 activation on the regulation of...
17.
Leite P, Lima-Araujo K, Franca G, Lagrota-Candido J, Santos W, Quirico-Santos T
Arch Immunol Ther Exp (Warsz) . 2014 May; 62(6):483-91. PMID: 24830560
Sustained chronic inflammation induces activation of genes involved in cellular proliferation and apoptosis, thereby causing skeletal muscle degeneration. To investigate in vitro effects of isolated pentacyclic triterpenes from Eugenia punicifolia...
18.
da Fonseca C, Teixeira R, Silva J, da Gama Fischer J, Meirelles O, Landeiro J, et al.
Anticancer Res . 2013 Dec; 33(12):5625-31. PMID: 24324108
Aim: This retrospective study aimed to evaluate the long-term response and toxicity of recurrent malignant glioma patients to inhalation chemotherapy with perillyl alcohol (POH). Patients And Methods: The cohort included...
19.
Salazar M, da Silva R, da Fonseca C, Lagrota-Candido J, Quirico-Santos T
Arch Immunol Ther Exp (Warsz) . 2013 Nov; 62(1):59-66. PMID: 24257817
Perillyl alcohol (POH) presents antitumoral activity but clinical application is hampered by adverse effects following oral administration. This work aimed to verify the cytotoxic effect of intranasal POH administration in...
20.
Quirico-Santos T, Nascimento Mello A, Casimiro Gomes A, de Carvalho L, de Souza J, Alves-Leon S
Brain Res . 2013 Oct; 1538:172-81. PMID: 24095794
Inflammation influences the pathogenesis of seizures by boosting neuronal degeneration of temporal lobe epilepsy with hippocampal sclerosis (TLE-HS). This work aimed to determine the activity of metalloproteases (MMPs) in brain...