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Theresa M Kisko

Explore the profile of Theresa M Kisko including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 204
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Recent Articles
1.
Gilardi C, Martins H, Levone B, Bianco A, Bicker S, Germain P, et al.
EMBO Rep . 2025 Mar; PMID: 40065182
Mood disorders (MDs) are caused by an interplay of genetic and environmental (GxE) risk factors. However, molecular pathways engaged by GxE risk factors are poorly understood. Using small-RNA sequencing in...
2.
Konigstein D, Fender H, Plackic J, Kisko T, Wohr M, Kockskamper J
Int J Mol Sci . 2025 Jan; 25(24. PMID: 39769475
encodes the α1c subunit of the L-type Ca channel, Cav1.2. Ventricular myocytes from haploinsufficient () rats exhibited reduced expression of Cav1.2 but an apparently normal sarcolemmal Ca influx with an...
3.
Bogdan R, Kayumova R, Schwarting R, Wohr M, Kisko T
Front Behav Neurosci . 2023 Aug; 17:1190272. PMID: 37600756
Background: Healthy brain development depends on early social practices and experiences. The risk gene is implicated in numerous neuropsychiatric disorders, in which key characteristics include deficits in social functioning and...
4.
Fender H, Walter K, Kiper A, Plackic J, Kisko T, Braun M, et al.
Int J Mol Sci . 2023 Jun; 24(12). PMID: 37372947
encodes the pore-forming α1C subunit of the L-type Ca channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient rats represent a recently developed...
5.
Martins H, Gilardi C, Sungur A, Winterer J, Pelzl M, Bicker S, et al.
EMBO Rep . 2022 Aug; 23(10):e54420. PMID: 35969184
Bipolar disorder (BD) is a chronic mood disorder characterized by manic and depressive episodes. Dysregulation of neuroplasticity and calcium homeostasis are frequently observed in BD patients, but the underlying molecular...
6.
Wohr M, Kisko T, Schwarting R
Brain Sci . 2021 Jun; 11(6). PMID: 34072335
The top-ranked cross-disorder risk gene is strongly associated with multiple neuropsychiatric dysfunctions. In a recent series of studies, we applied a genomically informed approach and contributed extensively to the behavioral...
7.
Kisko T, Schwarting R, Wohr M
Dev Psychobiol . 2020 Jun; 63(2):262-276. PMID: 32506508
Sexual dimorphisms are widespread in the animal kingdom. At the behavioral level, there is evidence for sex differences in social play behavior. In rats, males typically engage more in rough-and-tumble...
8.
Redecker T, Kisko T, Wohr M, Schwarting R
Physiol Behav . 2020 May; 223:112974. PMID: 32473156
The cross-disorder risk gene CACNA1C is strongly involved in the etiology of all major neuropsychiatric disorders, with women often being more affected by CACNA1C mutations than men. Human neuroimaging studies...
9.
Wohr M, Willadsen M, Kisko T, Schwarting R, Fendt M
Prog Neuropsychopharmacol Biol Psychiatry . 2019 Dec; 99:109849. PMID: 31862418
Deficits in processing social signals leads to reduced social functioning and is typically associated with neuropsychiatric disorders, including autism spectrum disorder, schizophrenia, and major depressive disorder. The cross-disorder risk gene...
10.
Michels S, Dolga A, Braun M, Kisko T, Sungur A, Witt S, et al.
Front Cell Neurosci . 2019 Nov; 13:483. PMID: 31708752
The pathophysiology of neuropsychiatric disorders involves complex interactions between genetic and environmental risk factors. Confirmed by several genome-wide association studies, represents one of the most robustly replicated psychiatric risk genes....