Theodore T Diakov
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Explore the profile of Theodore T Diakov including associated specialties, affiliations and a list of published articles.
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6
Citations
228
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Recent Articles
1.
Smardon A, Nasab N, Tarsio M, Diakov T, Kane P
J Biol Chem
. 2015 Sep;
290(46):27511-23.
PMID: 26405040
The RAVE complex (regulator of the H(+)-ATPase of vacuolar and endosomal membranes) is required for biosynthetic assembly and glucose-stimulated reassembly of the yeast vacuolar H(+)-ATPase (V-ATPase). Yeast RAVE contains three...
2.
Li S, Diakov T, Xu T, Tarsio M, Zhu W, Couoh-Cardel S, et al.
Mol Biol Cell
. 2014 Feb;
25(8):1251-62.
PMID: 24523285
Vacuolar proton-translocating ATPases (V-ATPases) are highly conserved, ATP-driven proton pumps regulated by reversible dissociation of its cytosolic, peripheral V1 domain from the integral membrane V(o) domain. Multiple stresses induce changes...
3.
Smardon A, Diab H, Tarsio M, Diakov T, Nasab N, West R, et al.
Mol Biol Cell
. 2013 Dec;
25(3):356-67.
PMID: 24307682
The regulator of ATPase of vacuoles and endosomes (RAVE) complex is implicated in vacuolar H(+)-translocating ATPase (V-ATPase) assembly and activity. In yeast, rav1 mutants exhibit a Vma(-) growth phenotype characteristic...
4.
Diakov T, Tarsio M, Kane P
J Vis Exp
. 2013 May;
(74).
PMID: 23629151
Vacuolar and cytosolic pH are highly regulated in yeast cells and occupy a central role in overall pH homeostasis. We describe protocols for ratiometric measurement of pH in vivo using...
5.
Li S, Diakov T, Rizzo J, Kane P
Eukaryot Cell
. 2012 Jan;
11(3):282-91.
PMID: 22210831
Hyperosmotic stress activates an array of cellular detoxification mechanisms, including the high-osmolarity glycerol (HOG) pathway. We report here that vacuolar H(+)-ATPase (V-ATPase) activity helps provide osmotic tolerance in Saccharomyces cerevisiae....
6.
Diakov T, Kane P
J Biol Chem
. 2010 Jun;
285(31):23771-8.
PMID: 20511227
Vacuolar proton-translocating ATPases (V-ATPases) are responsible for organelle acidification in all eukaryotic cells. The yeast V-ATPase, known to be regulated by reversible disassembly in response to glucose deprivation, was recently...