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Theodore R Hobbs

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Articles 19
Citations 223
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Recent Articles
1.
Streblow D, Hirsch A, Stanton J, Lewis A, Colgin L, Hessell A, et al.
Nat Commun . 2023 Nov; 14(1):7062. PMID: 37923717
Passively administered monoclonal antibodies (mAbs) given before or after viral infection can prevent or blunt disease. Here, we examine the efficacy of aerosol mAb delivery to prevent infection and disease...
2.
Piekarski N, Hobbs T, Jacob D, Schwartz T, Burch F, Mishler E, et al.
Animals (Basel) . 2023 Oct; 13(19). PMID: 37835623
Obtaining quality oocytes is a prerequisite for ART-based studies. Here we describe a method for transabdominal ultrasound-guided (US) oocyte retrieval in rhesus macaques () and compare it to the standard...
3.
Wu H, Busman-Sahay K, Weber W, Waytashek C, Boyle C, Bateman K, et al.
Immunity . 2023 May; 56(7):1649-1663.e5. PMID: 37236188
Allogeneic hematopoietic stem cell transplantation (alloHSCT) from donors lacking C-C chemokine receptor 5 (CCR5) can cure HIV, yet mechanisms remain speculative. To define how alloHSCT mediates HIV cure, we performed...
4.
Muller M, Hodovan J, Ozawa K, Hagen M, Hobbs T, Templon J, et al.
Ultrasound Med Biol . 2022 Aug; 48(10):2146-2153. PMID: 35934554
Ultrasound (US) generated by catheters used clinically for US-facilitated thrombolysis can release shear-dependent vasodilators from endothelial and red blood cells. We hypothesized that catheter-based US in the pulmonary artery (PA)...
5.
Muller M, Ozawa K, Hodovan J, Hagen M, Giraud D, Qi Y, et al.
Ultrasound Med Biol . 2021 May; 47(8):2277-2285. PMID: 33934942
Ultrasound (US) is known to stimulate endogenous shear-dependent pathways, and can lower microvascular resistance through mediators that are conducted downstream from US exposure. We hypothesized that endovascular US, already in...
6.
Moats C, Randall K, Swanson T, Crank H, Armantrout K, Barber-Axthelm A, et al.
Comp Med . 2020 Nov; 70(6):520-525. PMID: 33153516
Nonbronchoscopic bronchoalveolar lavage (NB-BAL) is a minimally invasive diagnostic and research tool used to sample the cells of lower airways and alveoli without using a bronchoscope. Our study compared NB-BAL...
7.
Wu H, Weber W, Shriver-Munsch C, Swanson T, Northrup M, Price H, et al.
Xenotransplantation . 2020 Jan; 27(4):e12578. PMID: 31930750
Allogeneic hematopoietic stem cell transplantation (HSCT) and xenotransplantation are accompanied by viral reactivations and virus-associated complications resulting from immune deficiency. Here, in a Mauritian cynomolgus macaque model of fully MHC-matched...
8.
Bahjat F, West G, Kohama S, Glynn C, Urbanski H, Hobbs T, et al.
Transl Stroke Res . 2017 Apr; 8(4):322-333. PMID: 28378315
Ischemia-reperfusion brain injury can be iatrogenically induced secondary to life-saving procedures. Prophylactic treatment of these patients offers a promising prevention for lifelong complications. We postulate that a cytosine-guanine (CpG) oligodeoxynucleotide...
9.
Hobbs T, Blue S, Park B, Greisel J, Conn P, Pau F
J Am Assoc Lab Anim Sci . 2015 Dec; 54(6):687-93. PMID: 26632777
Most biomedical facilities that use rhesus macaques (Macaca mulatta) limit the amount of blood that may be collected for experimental purposes. These limits typically are expressed as a percentage of...
10.
Tardif S, Coleman K, Hobbs T, Lutz C
ILAR J . 2013 Nov; 54(2):234-45. PMID: 24174445
This article will detail some of the issues that must be considered as institutional animal care and use committees (IACUCs) review the use of nonhuman primates (NHPs) in research. As...