Theo Verrips
Overview
Explore the profile of Theo Verrips including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
968
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0
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Recent Articles
1.
Schriek A, van Haaren M, Poniman M, Dekkers G, Bentlage A, Grobben M, et al.
Front Immunol
. 2022 Dec;
13:1091668.
PMID: 36483568
[This corrects the article DOI: 10.3389/fimmu.2022.893648.].
2.
Schriek A, van Haaren M, Poniman M, Dekkers G, Bentlage A, Grobben M, et al.
Front Immunol
. 2022 Jun;
13:893648.
PMID: 35651621
The most effective treatment for HIV-1, antiretroviral therapy, suppresses viral replication and averts the disease from progression. Nonetheless, there is a need for alternative treatments as it requires daily administration...
3.
Zhou T, Chen L, Gorman J, Wang S, Kwon Y, Lin B, et al.
Structure
. 2022 Apr;
30(6):862-875.e4.
PMID: 35413243
Nanobodies can achieve remarkable neutralization of genetically diverse pathogens, including HIV-1. To gain insight into their recognition, we determined crystal structures of four llama nanobodies (J3, A12, C8, and D7),...
4.
Strokappe N, Hock M, Rutten L, McCoy L, Back J, Caillat C, et al.
Antibodies (Basel)
. 2019 Sep;
8(2).
PMID: 31544844
Broad and potent neutralizing llama single domain antibodies (VHH) against HIV-1 targeting the CD4 binding site (CD4bs) have previously been isolated upon llama immunization. Here we describe the epitopes of...
5.
Hout A, Klarenbeek A, Bobkov V, Doijen J, Arimont M, Zhao C, et al.
Biochem Pharmacol
. 2018 Oct;
158:402-412.
PMID: 30342024
The chemokine receptor CXCR4 and its ligand CXCL12 contribute to a variety of human diseases, such as cancer. CXCR4 is also a major co-receptor facilitating HIV entry. Accordingly, CXCR4 is...
6.
Zhong L, Huang X, Rodrigues E, Leijten J, Verrips T, El Khattabi M, et al.
Stem Cells Dev
. 2016 Oct;
25(23):1808-1817.
PMID: 27733096
Hypertrophic differentiation occurs during in vitro chondrogenesis of mesenchymal stem cells (MSCs), decreasing the quality of the cartilage construct. Previously we identified WNT pathway antagonists Dickkopf 1 homolog (DKK1) and...
7.
Andersen K, Strokappe N, Hultberg A, Truusalu K, Smidt I, Mikelsaar R, et al.
Infect Immun
. 2015 Nov;
84(2):395-406.
PMID: 26573738
Clostridium difficile is the primary cause of nosocomial antibiotic-associated diarrhea in the Western world. The major virulence factors of C. difficile are two exotoxins, toxin A (TcdA) and toxin B...
8.
Klarenbeek A, El Mazouari K, Desmyter A, Blanchetot C, Hultberg A, De Jonge N, et al.
MAbs
. 2015 May;
7(4):693-706.
PMID: 26018625
Camelid immunoglobulin variable (IGV) regions were found homologous to their human counterparts; however, the germline V repertoires of camelid heavy and light chains are still incomplete and their therapeutic potential...
9.
McCoy L, Groppelli E, Blanchetot C, de Haard H, Verrips T, Rutten L, et al.
Retrovirology
. 2015 Feb;
11:83.
PMID: 25700025
Background: Direct cell-cell spread of HIV-1 is a very efficient mode of viral dissemination, with increasing evidence suggesting that it may pose a considerable challenge to controlling viral replication in...
10.
McCoy L, Rutten L, Frampton D, Anderson I, Granger L, Bashford-Rogers R, et al.
PLoS Pathog
. 2014 Dec;
10(12):e1004552.
PMID: 25522326
To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV-1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has...