Theo N Kirkland
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Explore the profile of Theo N Kirkland including associated specialties, affiliations and a list of published articles.
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25
Citations
853
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Recent Articles
11.
Kirkland T
Med Mycol
. 2016 Apr;
54(6):648-53.
PMID: 27118798
The small number of fungi that commonly cause disease in normal people share the capacity to grow as mycelia in the soil at 25°C and as yeast (or spherules) in...
12.
Viriyakosol S, Singhania A, Fierer J, Goldberg J, Kirkland T, Woelk C
BMC Microbiol
. 2013 May;
13:121.
PMID: 23714098
Background: Coccidioides immitis is a dimorphic fungus that causes disease in mammals, including human beings. It grows as a mycelium containing arthroconidia in the soil and in the host arthroconidia...
13.
Woelk C, Zhang J, Walls L, Viriyakosol S, Singhania A, Kirkland T, et al.
BMC Microbiol
. 2012 Sep;
12:218.
PMID: 23006927
Background: Coccidioidomycosis results from airborne infections caused by either Coccidioides immitis or C. posadasii. Both are pathogenic fungi that live in desert soil in the New World and can infect...
14.
Margolis D, Viriyakosol S, Fierer J, Kirkland T
BMC Microbiol
. 2011 Apr;
11:71.
PMID: 21481258
Background: Coccidioidomycosis is usually a self-limited infection in immunocompentent people. In immunocompentent human beings second infections due to Coccidioides are very rare, indicating that recovery from infection results in protective...
15.
Neafsey D, Barker B, Sharpton T, Stajich J, Park D, Whiston E, et al.
Genome Res
. 2010 Jun;
20(7):938-46.
PMID: 20516208
We have sequenced the genomes of 18 isolates of the closely related human pathogenic fungi Coccidioides immitis and Coccidioides posadasii to more clearly elucidate population genomic structure, bringing the total...
16.
Asolkar R, Kirkland T, Jensen P, Fenical W
J Antibiot (Tokyo)
. 2009 Nov;
63(1):37-9.
PMID: 19927167
No abstract available.
17.
Sharpton T, Stajich J, Rounsley S, Gardner M, Wortman J, Jordar V, et al.
Genome Res
. 2009 Sep;
19(10):1722-31.
PMID: 19717792
While most Ascomycetes tend to associate principally with plants, the dimorphic fungi Coccidioides immitis and Coccidioides posadasii are primary pathogens of immunocompetent mammals, including humans. Infection results from environmental exposure...
18.
Viriyakosol S, McCray P, Ashbaugh M, Chu J, Jia H, Weiss J, et al.
Hybridoma (Larchmt)
. 2007 Jan;
25(6):349-57.
PMID: 17203997
Toll-like receptors (TLRs) are mammalian innate immune recognition receptors that are activated by pathogen associated molecular patterns (PAMPs). TLR4 is the signaling molecule of the lipopolysaccharide (LPS) receptor complex. TLR4...
19.
Shubitz L, Yu J, Hung C, Kirkland T, Peng T, Perrill R, et al.
Vaccine
. 2006 Jun;
24(31-32):5904-11.
PMID: 16759762
Two recombinant antigens which individually protect mice from lethal intranasal infection were studied in combination, either as a mixture of two separately expressed proteins or as a single chimeric expression...
20.
Viriyakosol S, Tobias P, Kirkland T
J Biol Chem
. 2006 Feb;
281(17):11955-64.
PMID: 16467306
Toll-like receptor 4 and MD-2 form a receptor for lipopolysaccharide (LPS), a major constituent of Gram-negative bacteria. MD-2 is a 20-25-kDa extracellular glycoprotein that binds to Tolllike receptor 4 (TLR4)...