Thea Sjogren
Overview
Explore the profile of Thea Sjogren including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
17
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Recent Articles
1.
Sjogren T, Islam S, Filippov I, Jebrzycka A, Sulen A, Breivik L, et al.
iScience
. 2024 Apr;
27(4):109610.
PMID: 38632993
Immune tolerance fails in autoimmune polyendocrine syndrome type 1 (APS-1) because of mutations. We have used single cell transcriptomics to characterize regulatory T cells (Tregs) sorted directly from blood and...
2.
Oftedal B, Sjogren T, Wolff A
Front Immunol
. 2024 Mar;
15:1327784.
PMID: 38455040
Type I interferons (IFN-I) are key immune messenger molecules that play an important role in viral defense. They act as a bridge between microbe sensing, immune function magnitude, and adaptive...
3.
Sjogren T, Bjune J, Husebye E, Oftedal B, Wolff A
Clin Exp Immunol
. 2023 Aug;
215(1):47-57.
PMID: 37578839
Primary adrenal insufficiency (PAI) is most often caused by an autoimmune destruction of the adrenal cortex resulting in failure to produce cortisol and aldosterone. The aetiology is thought to be...
4.
Wolff A, Hansen L, Grytaas M, Oftedal B, Breivik L, Zhou F, et al.
iScience
. 2023 Jun;
26(7):107084.
PMID: 37346050
A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of these antibodies has been associated with severe...
5.
Sjogren T, Bratland E, Royrvik E, Grytaas M, Benneche A, Knappskog P, et al.
J Autoimmun
. 2022 Oct;
133:102917.
PMID: 36191466
Background: Autoantibodies against type I interferons (IFN) alpha (α) and omega (ω), and interleukins (IL) 17 and 22 are a hallmark of autoimmune polyendocrine syndrome type 1 (APS-1), caused by...
6.
Berger A, Bratland E, Sjogren T, Heimli M, Tyssedal T, Bruserud O, et al.
Front Immunol
. 2021 Sep;
12:722860.
PMID: 34526996
Autoimmune polyendocrine syndrome type I (APS-1) is a monogenic model disorder of organ-specific autoimmunity caused by mutations in the gene. AIRE facilitates the expression of organ-specific transcripts in the thymus,...