Thanjavur S Ravikumar
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Explore the profile of Thanjavur S Ravikumar including associated specialties, affiliations and a list of published articles.
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28
Citations
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Recent Articles
11.
Wu R, Higuchi S, Dong W, Ji Y, Zhou M, Marini C, et al.
Mol Med
. 2008 Nov;
15(1-2):28-33.
PMID: 19009024
We recently demonstrated that early administration of rat adrenomedullin (AM), a vasoactive peptide, in combination with its binding protein (human AMBP-1) produces various beneficial effects in sepsis. Human AM is...
12.
Higuchi S, Wu R, Zhou M, Marini C, Ravikumar T, Wang P
Int J Clin Exp Pathol
. 2008 Sep;
1(5):409-18.
PMID: 18787625
Ischemia bowel remains a critical problem resulting in up to 80% mortality. The loss of gut barrier function plays an important role. Our previous studies have shown that administration of...
13.
Wu R, Dong W, Ji Y, Zhou M, Marini C, Ravikumar T, et al.
PLoS One
. 2008 Apr;
3(4):e2026.
PMID: 18431503
Background: Gut ischemia/reperfusion (I/R) injury is a serious condition in intensive care patients. Activation of immune cells adjacent to the huge endothelial cell surface area of the intestinal microvasculature produces...
14.
Wu R, Dong W, Qiang X, Ji Y, Cui T, Yang J, et al.
Peptides
. 2008 Apr;
29(7):1223-30.
PMID: 18403050
We recently discovered that vascular responsiveness to adrenomedullin (AM), a vasoactive hormone, decreases after hemorrhage, which is markedly improved by the addition of its binding protein AMBP-1. One obstacle hampering...
15.
Agaba E, Shamseddeen H, Sasthakonar V, Sivalingham V, Shah K, Ravikumar T, et al.
Am Surg
. 2007 Dec;
73(11):1140-3.
PMID: 18092650
Since its introduction in 2001, Wireless Video Capsule enteroscopy is gaining acceptance due to its high diagnostic potential and minimal risk. In some centers, it offers an alternative approach to...
16.
Miksa M, Wu R, Cui X, Dong W, Das P, Simms H, et al.
J Immunol
. 2007 Oct;
179(9):6263-72.
PMID: 17947702
Sepsis is a critical inflammatory condition from which numerous patients die due to multiple organ failure and septic shock. The vasoactive hormone adrenomedullin (AM) and its binding protein (AMBP-1) are...
17.
Wu R, Zhou M, Das P, Dong W, Ji Y, Yang D, et al.
Am J Physiol Endocrinol Metab
. 2007 Oct;
293(6):E1697-702.
PMID: 17911350
Our previous studies have shown that norepinephrine (NE) upregulates proinflammatory cytokines by activating alpha(2)-adrenoceptor. Therefore, modulation of the sympathetic nervous system represents a novel treatment for sepsis. We have also...
18.
Miksa M, Amin D, Wu R, Ravikumar T, Wang P
Mol Med
. 2007 Aug;
13(11-12):553-60.
PMID: 17673941
Clearance of apoptotic cells is crucial to maintain cellular function under normal and pathological conditions. We have recently shown that administration of immature dendritic cell-derived exosomes to septic animals promotes...
19.
Dwivedi A, Wu R, Nguyen E, Higuchi S, Wang H, Krishnasastry K, et al.
J Am Coll Surg
. 2007 Jul;
205(2):284-93.
PMID: 17660075
Background: Ischemic bowel remains a critical problem, resulting in up to 80% mortality. Acute lung injury, a common complication after intestinal ischemia/reperfusion (I/R), might be responsible for such a high...
20.
Wu R, Dong W, Zhou M, Zhang F, Marini C, Ravikumar T, et al.
Am J Respir Crit Care Med
. 2007 Jul;
176(8):805-13.
PMID: 17626913
Rationale: Our study has shown that plasma levels of ghrelin, a stomach-derived peptide, are significantly reduced in sepsis, and that ghrelin administration improves organ blood flow via a nuclear factor...