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Thanjavur S Ravikumar

Explore the profile of Thanjavur S Ravikumar including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 808
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Recent Articles
1.
Rajalatchumi A, Ravikumar T, Muruganandham K, Thulasingam M, Selvaraj K, Reddy M, et al.
J Nat Sci Biol Med . 2018 Feb; 9(1):14-18. PMID: 29456386
Introduction: Patient safety is a global concern and is the most important domains of health-care quality. Medical error is a major patient safety concern, causing increase in health-care cost due...
2.
Ravikumar T, Sharma C, Marini C, Steele Jr G, Ritter G, Barrera R, et al.
Ann Surg . 2010 Aug; 252(3):486-96. PMID: 20739849
Objectives: Authors hypothesized that building safe hospital systems to improve value-based surgical outcomes is predicated on workflow redesign for dynamic risk stratification, coupled with "real-time" mitigation of risk. We developed...
3.
Cui T, Miksa M, Wu R, Komura H, Zhou M, Dong W, et al.
Am J Respir Crit Care Med . 2009 Nov; 181(3):238-46. PMID: 19892861
Rationale: Milk fat globule epidermal growth factor 8 (MFG-E8) is a potent opsonin for the clearance of apoptotic cells and is produced by mononuclear cells of immune competent organs including...
4.
Miksa M, Wu R, Dong W, Komura H, Amin D, Ji Y, et al.
J Immunol . 2009 Oct; 183(9):5983-90. PMID: 19812188
Sepsis, a highly lethal systemic inflammatory syndrome, is associated with increases of proinflammatory cytokines (e.g., TNF-alpha, HMGB1) and the accumulation of apoptotic cells that have the potential to be detrimental....
5.
Shah K, Wu R, Jacob A, Blau S, Ji Y, Dong W, et al.
Mol Med . 2009 Sep; 15(11-12):407-14. PMID: 19779631
In the terrorist radiation exposure scenario, radiation victims are likely to suffer from additional injuries such as sepsis. Our previous studies have shown that ghrelin is protective in sepsis. However,...
6.
Wu R, Zhou M, Dong W, Ji Y, Miksa M, Marini C, et al.
Ann Surg . 2009 Jun; 250(1):126-33. PMID: 19561473
Objective: To test the hypothesis that hyporesponsiveness to ghrelin due to reduced growth hormone (GH) contributes to the aging-related hyperinflammatory state in sepsis. Summary Background Data: Sepsis and septic shock...
7.
Wu R, Dong W, Qiang X, Wang H, Blau S, Ravikumar T, et al.
Crit Care Med . 2009 Jun; 37(8):2421-6. PMID: 19531942
Objectives: We have recently shown that ghrelin, a novel orexigenic hormone, is reduced in sepsis. Ghrelin treatment, mediated through ghrelin receptors in the brain, attenuates sepsis-induced inflammation and mortality. Gut...
8.
Miksa M, Das P, Zhou M, Wu R, Dong W, Ji Y, et al.
PLoS One . 2009 May; 4(5):e5504. PMID: 19430535
Background: Norepinephrine (NE) modulates the responsiveness of macrophages to proinflammatory stimuli through the activation of adrenergic receptors (ARs). Being part of the stress response, early increases of NE in sepsis...
9.
Yang J, Wu R, Qiang X, Zhou M, Dong W, Ji Y, et al.
Ann Surg . 2009 Feb; 249(2):310-7. PMID: 19212187
Objective: To determine whether administration of a vasoactive peptide, human adrenomedullin (AM), in combination with its binding protein (ie, AMBP-1), prevents or minimizes hepatic ischemia-reperfusion (I/R) injury. Summary Background Data:...
10.
Miksa M, Amin D, Wu R, Jacob A, Zhou M, Dong W, et al.
Int J Mol Med . 2008 Nov; 22(6):743-8. PMID: 19020771
In sepsis, phagocytosis and the killing of bacteria by phagocytes are important. Similarly, the clearance of accumulating apoptotic cells is critical in maintaining normal immunity. Upon maturation, peritoneal macrophages (PM)...