Thairy Reyes Valero
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Explore the profile of Thairy Reyes Valero including associated specialties, affiliations and a list of published articles.
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4
Citations
62
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Recent Articles
1.
McCrink K, Brill A, Jafferjee M, Valero T, Marrero C, Rodriguez M, et al.
Pharmacogenomics
. 2016 Sep;
17(15):1611-1620.
PMID: 27643874
Aim: The β-adrenergic receptor (AR) Arg389Gly polymorphism affects efficacy of its procontractile signaling in cardiomyocytes and carriers' responses to β-blockers. To identify molecular mechanisms underlying functional differences between Arg389 and...
2.
Valero T, Sturchler E, Jafferjee M, Rengo G, Magafa V, Cordopatis P, et al.
Pharmacol Res Perspect
. 2016 Apr;
4(2):e00226.
PMID: 27069636
The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion induction, a steroid hormone that contributes to the pathology of postmyocardial infarction (MI) heart failure (HF), is mediated...
3.
GRK2 Up-Regulation Creates a Positive Feedback Loop for Catecholamine Production in Chromaffin Cells
Jafferjee M, Valero T, Marrero C, McCrink K, Brill A, Lymperopoulos A
Mol Endocrinol
. 2016 Feb;
30(3):372-81.
PMID: 26849467
Elevated sympathetic nervous system (SNS) activity aggravates several diseases, including heart failure. The molecular cause(s) underlying this SNS hyperactivity are not known. We have previously uncovered a neurohormonal mechanism, operating...
4.
Dabul S, Bathgate-Siryk A, Valero T, Jafferjee M, Sturchler E, McDonald P, et al.
Sci Rep
. 2015 Jan;
5:8116.
PMID: 25631300
The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion is mediated by either Gq/11 proteins or βarrestin1 (βarr1), both of which can couple to its type 1...