Teruo Kusano
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Explore the profile of Teruo Kusano including associated specialties, affiliations and a list of published articles.
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9
Citations
88
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Recent Articles
1.
Sato N, Kusano T, Nagata K, Okamoto K
Brain Res
. 2025 Jan;
1849():149444.
PMID: 39755194
The brain is an organ that consumes a substantial amount of oxygen, and a reduction in oxygen concentration can rapidly lead to significant and irreversible brain injury. The progression of...
2.
Kusano T, Nishino T, Okamoto K, Hille R, Nishino T
Redox Biol
. 2022 Dec;
59:102573.
PMID: 36525890
The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) occurs only in mammalian species. In fresh bovine milk, the enzyme exists predominantly as the oxidase form, in contrast to...
3.
Nasi S, Castelblanco M, Chobaz V, Ehirchiou D, So A, Bernabei I, et al.
Front Cell Dev Biol
. 2021 Feb;
9:612440.
PMID: 33634117
Pathologic calcification of cartilage consists of the formation of basic calcium phosphate (BCP) and/or calcium pyrophosphate dihydrate (CPPD) containing calcium crystals in mature hyaline or articular cartilage and is associated...
4.
Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, et al.
Nat Commun
. 2019 Oct;
10(1):4904.
PMID: 31659168
Xanthine oxidoreductase has been implicated in cancer. Nonetheless, the role played by its two convertible forms, xanthine dehydrogenase (XDH) and oxidase (XO) during tumorigenesis is not understood. Here we produce...
5.
Kato S, Kato M, Kusano T, Nishino T
J Neuropathol Exp Neurol
. 2016 Nov;
75(12):1124-1144.
PMID: 27815397
Amyotrophic lateral sclerosis (ALS), Lou Gehrig's disease, is a progressive fatal neurodegenerative disease that involves both upper and lower motor neurons. We orally administered 4 xanthine oxidoreductase (XOR) inhibitors to...
6.
Yamaguchi M, Okamoto K, Kusano T, Matsuda Y, Suzuki G, Fuse A, et al.
PLoS One
. 2015 Aug;
10(7):e0133980.
PMID: 26230326
We demonstrated that 3-nitrotyrosine and 4-hydroxy-2-nonenal levels in mouse brain were elevated from 1 h until 8 h after global brain ischemia for 14 min induced with the 3-vessel occlusion...
7.
Suzuki G, Okamoto K, Kusano T, Matsuda Y, Fuse A, Yokota H
Neurol Med Chir (Tokyo)
. 2015 Mar;
55(1):77-85.
PMID: 25744353
Global cerebral ischemia and reperfusion (I/R) often result in high mortality. Free radicals play an important role in global cerebral I/R. Xanthine oxidoreductase (XOR) inhibitors, such as allopurinol, have been...
8.
Matsuda Y, Suzuki G, Kusano T, Kawamoto Y, Yoshimura H, Fuse A, et al.
Pathol Int
. 2013 Nov;
63(9):448-56.
PMID: 24200156
Nestin, a class VI intermediate filament protein, is expressed by neuronal progenitor cells in the subventricular zone (SVZ). In the present study, we analyzed the nestin expression and phosphorylation levels...
9.
Okamoto K, Kusano T, Nishino T
Curr Pharm Des
. 2012 Nov;
19(14):2606-14.
PMID: 23116398
Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The...