Teruhito Yamashita
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Explore the profile of Teruhito Yamashita including associated specialties, affiliations and a list of published articles.
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38
Citations
1020
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Recent Articles
1.
Komatsu K, Ideno H, Nakashima K, Udagawa N, Kobayashi Y, Kimura H, et al.
FASEB J
. 2024 Jul;
38(13):e23779.
PMID: 38967255
Epigenetic modifications affect cell differentiation via transcriptional regulation. G9a/EHMT2 is an important epigenetic modifier that catalyzes the methylation of histone 3 lysine 9 (H3K9) and interacts with various nuclear proteins....
2.
Nakamura K, Koide M, Kobayashi Y, Yamashita T, Matsushita M, Yasuda H, et al.
J Periodontal Res
. 2023 May;
58(4):769-779.
PMID: 37154419
Background And Objective: Severe periodontitis causes alveolar bone resorption, resulting in tooth loss. Developments of tissue regeneration therapy that can restore alveolar bone mass are desired for periodontal disease. The...
3.
Hiraga T, Horibe K, Koide M, Yamashita T, Kobayashi Y
Cancer Sci
. 2023 Feb;
114(6):2460-2470.
PMID: 36840409
The secreted protein sclerostin is primarily produced by osteocytes and suppresses osteoblast differentiation and function by inhibiting the canonical Wnt signaling pathway. Genetic and pharmacological inhibition of sclerostin has been...
4.
Koide M, Yamashita T, Nakamura K, Yasuda H, Udagawa N, Kobayashi Y
Bone
. 2022 Apr;
160:116401.
PMID: 35381389
Bone formation by osteoblasts is achieved through remodeling-based bone formation (RBBF) and modeling-based bone formation (MBBF). The former is when bone formation occurs after osteoclastic bone resorption to maintain bone...
5.
Uehara S, Mukai H, Yamashita T, Koide M, Murakami K, Udagawa N, et al.
J Bone Miner Metab
. 2022 Jan;
40(2):251-261.
PMID: 35028715
Introduction: The long-term inhibition of bone resorption suppresses new bone formation because these processes are coupled during physiological bone remodeling. The development of anti-bone-resorbing agents that do not suppress bone...
6.
Udagawa N, Koide M, Nakamura M, Nakamichi Y, Yamashita T, Uehara S, et al.
J Bone Miner Metab
. 2020 Oct;
39(1):19-26.
PMID: 33079279
Introduction: In bone tissue, bone resorption by osteoclasts and bone formation by osteoblasts are repeated continuously. Osteoclasts are multinucleated cells that derive from monocyte-/macrophage-lineage cells and resorb bone. In contrast,...
7.
Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, et al.
Sci Rep
. 2020 Aug;
10(1):13751.
PMID: 32792620
Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined...
8.
Shimada A, Ideno H, Arai Y, Komatsu K, Wada S, Yamashita T, et al.
J Bone Miner Res
. 2018 Apr;
33(8):1532-1543.
PMID: 29694681
Little is known about the molecular mechanisms of enthesis formation in mature animals. Here, we report that annexin A5 (Anxa5) plays a critical role in the regulation of bone ridge...
9.
Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, et al.
Sci Signal
. 2017 Aug;
10(494).
PMID: 28851822
Cytoskeletal reorganization in osteoclasts to form actin rings is necessary for these cells to attach to bone and resorb bone matrices. We delineated the pathway through which Wnt5a signaling through...
10.
Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, et al.
PLoS One
. 2017 Jul;
12(7):e0181126.
PMID: 28708884
The Janus kinases (Jaks) are hubs in the signaling process of more than 50 cytokine or hormone receptors. However, the function of Jak in bone metabolism remains to be elucidated....