Teresia Osborn
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Explore the profile of Teresia Osborn including associated specialties, affiliations and a list of published articles.
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10
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973
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Recent Articles
1.
Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al.
Stem Cells
. 2019 Aug;
37(10):1293-1306.
PMID: 31381839
Cell state-, developmental stage-, and lineage-specific combinatorial expression of cluster of differentiation (CD) molecules enables the identification of cellular subsets via multicolor flow cytometry. We describe an exhaustive characterization of...
2.
Osborn T, Hallett P
Cell Stem Cell
. 2017 Jan;
20(1):11-12.
PMID: 28061349
Transplantation of human pluripotent stem cell-derived dopaminergic neurons is a promising approach to treating Parkinson's disease. In this issue of Cell Stem Cell, Kee et al. (2017) and Kirkeby et ...
3.
Smith G, Rocha E, Rooney T, Barneoud P, McLean J, Beagan J, et al.
PLoS One
. 2015 Mar;
10(3):e0121072.
PMID: 25815475
Dopaminergic neurons in the substantia nigra pars compacta (SNpc) are characterized by the expression of genes required for dopamine synthesis, handling and reuptake and the expression of these genes is...
4.
Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, et al.
Stem Cells
. 2013 May;
31(8):1548-62.
PMID: 23666606
The main motor symptoms of Parkinson's disease are due to the loss of dopaminergic (DA) neurons in the ventral midbrain (VM). For the future treatment of Parkinson's disease with cell...
5.
Cooper O, Seo H, Andrabi S, Guardia-Laguarta C, Graziotto J, Sundberg M, et al.
Sci Transl Med
. 2012 Jul;
4(141):141ra90.
PMID: 22764206
Parkinson's disease (PD) is a common neurodegenerative disorder caused by genetic and environmental factors that results in degeneration of the nigrostriatal dopaminergic pathway in the brain. We analyzed neural cells...
6.
Deleidi M, Hargus G, Hallett P, Osborn T, Isacson O
Stem Cells
. 2011 May;
29(7):1052-63.
PMID: 21608081
Immune rejection and risk of tumor formation are perhaps the greatest hurdles in the field of stem cell transplantation. Here, we report the generation of several lines of induced pluripotent...
7.
Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, et al.
EMBO J
. 2010 Oct;
29(21):3593-606.
PMID: 20935625
The large GTPase dynamin assembles into higher order structures that are thought to promote endocytosis. Dynamin also regulates the actin cytoskeleton through an unknown, GTPase-dependent mechanism. Here, we identify a...
8.
Hedlund E, Karlsson M, Osborn T, Ludwig W, Isacson O
Brain
. 2010 Sep;
133(Pt 8):2313-30.
PMID: 20826431
Different somatic motor neuron subpopulations show a differential vulnerability to degeneration in diseases such as amyotrophic lateral sclerosis, spinal muscular atrophy and spinobulbar muscular atrophy. Studies in mutant superoxide dismutase...
9.
Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, et al.
Proc Natl Acad Sci U S A
. 2010 Aug;
107(36):15921-6.
PMID: 20798034
Recent advances in deriving induced pluripotent stem (iPS) cells from patients offer new possibilities for biomedical research and clinical applications, as these cells could be used for autologous transplantation. We...
10.
Cooper O, Hargus G, Deleidi M, Blak A, Osborn T, Marlow E, et al.
Mol Cell Neurosci
. 2010 Jul;
45(3):258-66.
PMID: 20603216
The cardinal motor symptoms of Parkinson's disease (PD) are caused by the vulnerability to dysfunction and degeneration of ventral midbrain (VM) dopaminergic (DA) neurons. A major limitation for experimental studies...