Taylor Bertucci
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Explore the profile of Taylor Bertucci including associated specialties, affiliations and a list of published articles.
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77
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Recent Articles
1.
Bhattarai P, Yilmaz E, Cakir E, Korkmaz H, Lee A, Ma Y, et al.
bioRxiv
. 2025 Feb;
PMID: 39975303
Graphical Abstract: Accessibility Text: This image illustrates the effects of different APOE isoforms (ApoE-ε3 and ApoE-ε4) on blood-brain barrier (BBB) integrity, focusing on the molecular interactions between astrocytes and endothelial...
2.
DBrant L, Rugenstein N, Na S, Miller M, Czajka T, Trudeau N, et al.
bioRxiv
. 2024 Jun;
PMID: 38854137
Tau protein aggregation is a hallmark of several neurodegenerative diseases, including Alzheimer's disease, frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP), spurring development of tau-lowering therapeutic strategies. Here, we report...
3.
Pesantez Torres F, Tokranova N, Amodeo E, Bertucci T, Kiehl T, Xie Y, et al.
Biosens Bioelectron
. 2023 Oct;
242:115749.
PMID: 37839350
The biocompatibility of materials used in electronic devices is critical for the development of implantable devices like pacemakers and neuroprosthetics, as well as in future biomanufacturing. Biocompatibility refers to the...
4.
Bertucci T, Kakarla S, Winkelman M, Lane K, Stevens K, Lotz S, et al.
APL Bioeng
. 2023 Aug;
7(3):036107.
PMID: 37564277
During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This...
5.
Bertucci T, Bowles K, Lotz S, Qi L, Stevens K, Goderie S, et al.
bioRxiv
. 2023 Jul;
PMID: 37503195
Cerebral cortical-enriched organoids derived from human pluripotent stem cells (hPSCs) are valuable models for studying neurodevelopment, disease mechanisms, and therapeutic development. However, recognized limitations include the high variability of organoids...
6.
Glasauer S, Goderie S, Rauch J, Guzman E, Audouard M, Bertucci T, et al.
Stem Cell Reports
. 2022 Aug;
17(9):2127-2140.
PMID: 35985329
Mutations in the MAPT gene that encodes tau lead to frontotemporal dementia (FTD) with pathology evident in both cerebral neurons and glia. Human cerebral organoids (hCOs) from individuals harboring pathogenic...
7.
Bertucci T, Kakarla S, Kim D, Dai G
Methods Mol Biol
. 2021 Sep;
2375:1-12.
PMID: 34591294
Vasculature plays a vital role in human biology as blood vessels transport nutrients and oxygen throughout the body. Endothelial cells (ECs), specifically, are key as they maintain barrier functions between...
8.
Bowles K, Silva M, Whitney K, Bertucci T, Berlind J, Lai J, et al.
Cell
. 2021 Jul;
184(17):4547-4563.e17.
PMID: 34314701
Frontotemporal dementia (FTD) because of MAPT mutation causes pathological accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used human induced pluripotent stem cell (iPSC)-derived cerebral organoids...