Tatyana Vikulina
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Explore the profile of Tatyana Vikulina including associated specialties, affiliations and a list of published articles.
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18
Citations
359
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Recent Articles
1.
Dabeer S, Tripathi A, Weiss D, Vikulina T, Ofotokun I, Weitzmann M
J Infect Dis
. 2024 Dec;
PMID: 39726127
Background: Antiretroviral therapy (ART) causes osteoporosis and bone fractures, increasing morbidity and mortality in people living with HIV (PLH). ART induces immune reconstitution bone loss (IRBL), an inflammatory reaction associated...
2.
Tripathi A, Dabeer S, Song J, Vikulina T, Roser-Page S, Alvarez J, et al.
Cell Death Dis
. 2024 Dec;
15(12):907.
PMID: 39695103
Sickle cell disease (SCD) is a severe hematological disorder characterized by erythrocyte sickling that causes significant morbidity and mortality. Skeletal complications of SCD include a high incidence of bone loss,...
3.
Roser-Page S, Weiss D, Vikulina T, Yu M, Pacifici R, Weitzmann M
JBMR Plus
. 2022 Jul;
6(7):e10636.
PMID: 35866149
Cyclic adenosine monophosphate (cAMP)-dependent phosphodiesterase (PDE) inhibitors such as pentoxifylline (PTX) suppress cAMP degradation and promote cAMP-dependent signal transduction. PDE inhibitors increase bone formation and bone mass in preclinical models...
4.
Weitzmann M, Weiss D, Vikulina T, Roser-Page S, Yu K, McGee-Lawrence M, et al.
J Infect Dis
. 2021 Dec;
226(1):38-48.
PMID: 34962571
Background: Immune reconstitution bone loss (IRBL) is a common side-effect of antiretroviral therapy (ART) in people with human immunodeficiency virus (PWH). Immune reconstitution bone loss acts through CD4+ T-cell/immune reconstitution-induced...
5.
Weitzmann M, Roser-Page S, Vikulina T, Weiss D, Hao L, Baldwin W, et al.
Blood Adv
. 2019 Feb;
3(3):288-300.
PMID: 30700417
Hemophilia A (HA), a rare X-linked recessive genetic disorder caused by insufficient blood clotting factor VIII, leaves affected individuals susceptible to spontaneous and traumatic hemorrhage. Although males generally exhibit severe...
6.
Roser-Page S, Vikulina T, Yu K, McGee-Lawrence M, Weitzmann M
Rheumatology (Oxford)
. 2018 Mar;
57(6):1105-1114.
PMID: 29522194
Objective: Immunosuppressive biologics are used in the management of RA and additional immunomodulators are under investigation including modulators of the CD40/CD40 ligand (CD40L) costimulation pathway. Tampering with immune function can...
7.
Roser-Page S, Vikulina T, Weiss D, Habib M, Beck Jr G, Pacifici R, et al.
Ann N Y Acad Sci
. 2018 Mar;
1415(1):21-33.
PMID: 29500936
Activated lymphocytes promote inflammation and bone destruction in rheumatoid arthritis (RA), making T cells and B cells therapeutic targets. Indeed, pharmacological blockade of CD28 costimulation using CTLA-4Ig (abatacept), approved for...
8.
Weitzmann M, Vikulina T, Roser-Page S, Yamaguchi M, Ofotokun I
J Infect Dis
. 2017 Oct;
216(9):1070-1079.
PMID: 28968828
Background: Bone loss occurs in human immunodeficiency virus (HIV) infection but paradoxically is intensified by HIV-associated antiretroviral therapy (ART), resulting in an increased fracture incidence that is largely independent of...
9.
Ofotokun I, Titanji K, Vunnava A, Roser-Page S, Vikulina T, Villinger F, et al.
AIDS
. 2016 Jan;
30(3):405-14.
PMID: 26760232
Objective: Antiretroviral therapy (ART) paradoxically intensifies bone loss in the setting of HIV infection. Although the extent of bone loss varies, it occurs with virtually all ART types, suggesting a...
10.
Ofotokun I, Titanji K, Vikulina T, Roser-Page S, Yamaguchi M, Zayzafoon M, et al.
Nat Commun
. 2015 Sep;
6:8282.
PMID: 26392000
HIV infection causes bone loss. We previously reported that immunosuppression-mediated B-cell production of receptor activator of NF-κB ligand (RANKL) coupled with decline in osteoprotegerin correlate with decreased bone mineral density...