Tatsuya Sawasaki
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Explore the profile of Tatsuya Sawasaki including associated specialties, affiliations and a list of published articles.
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191
Citations
2929
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Recent Articles
1.
Lin X, Bai Y, Wang S, Nozawa A, Sawasaki T, Masatani T, et al.
Cells
. 2025 Jan;
14(2).
PMID: 39851549
The autophagy-related ubiquitin-like conjugation systems, the ATG8 and ATG12 systems, are universally conserved in eukaryotes. However, the covalent bond in the ATG12 system has recently been shown to be evolutionarily...
2.
Yusuf A, Wakaya K, Sakamoto T, Uemura T, Okamura K, Ramadan A, et al.
Plant Cell Environ
. 2024 Dec;
PMID: 39722556
Histone modification is a cellular process for transcriptional regulation. In herbivore-damaged plants, activation of genes involved in defence responses is required for antiherbivore properties, but little is known about how...
3.
Yamashita M, Ogawa C, Zhang B, Kobayashi T, Nomura A, Barker C, et al.
Nat Commun
. 2024 Nov;
15(1):10129.
PMID: 39613744
Despite its broad application in in vitro studies, the application of targeted protein degradation (TPD) to animal models faces considerable challenges. Here, we develop inducible and cell-type specific TPD systems...
4.
Desaki Y, Kato T, Nemoto K, Nozawa A, Uemura T, Ninomiya N, et al.
J Plant Res
. 2024 Oct;
138(1):95-103.
PMID: 39419929
Plants defend themselves against herbivores by recognizing herbivore-derived elicitors and activating intracellular signaling. In Arabidopsis, the receptor-like kinase HAK1 recognizes the poly-saccharide elicitor (FrA) from Spodoptera litura larvae, leading to...
5.
Shibuya K, Nozawa A, Takahashi C, Sawasaki T
Nat Plants
. 2024 Aug;
10(9):1377-1388.
PMID: 39209993
Petal senescence in flowering plants is a type of programmed cell death with highly regulated onset and progression. A NAM/ATAF1,2/CUC2 transcription factor, EPHEMERAL1 (EPH1), has been identified as a key...
6.
Kaneko N, Kurata M, Yamamoto T, Sakamoto A, Takada Y, Kosako H, et al.
J Immunol
. 2024 May;
213(1):86-95.
PMID: 38787200
The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3, also called cryopyrin) inflammasome is an intracellular innate immune complex, which consists of the pattern-recognition receptor NLRP3, the adaptor apoptosis-assciated...
7.
Ueda R, Hashimoto R, Fujii Y, Menezes J, Takahashi H, Takeda H, et al.
Membranes (Basel)
. 2024 Feb;
14(2).
PMID: 38392670
Lysosomal degradation of tyrosinase, a pivotal enzyme in melanin synthesis, negatively impacts melanogenesis in melanocytes. Nevertheless, the precise molecular mechanisms by which lysosomes target tyrosinase have remained elusive. Here, we...
8.
Utsugi Y, Nishimura K, Yamanaka S, Nishino K, Kosako H, Sawasaki T, et al.
ACS Chem Biol
. 2024 Jan;
19(2):497-505.
PMID: 38270585
The chemogenetic control of cellular protein stability using degron tags is a powerful experimental strategy in biomedical research. However, this technique requires permanent fusion of the degron to a target...
9.
Yamada K, Shioya R, Nishino K, Furihata H, Hijikata A, Kaneko M, et al.
Nat Commun
. 2023 Dec;
14(1):8301.
PMID: 38097606
Receptor proteins, such as epidermal growth factor receptor (EGFR), interact with other proteins in the extracellular region of the cell membrane to drive intracellular signalling. Therefore, analysis of extracellular protein-protein...
10.
Li X, Nakashima K, Ito M, Matsuda M, Chida T, Sekihara K, et al.
Antiviral Res
. 2023 Nov;
220:105756.
PMID: 37992764
New antiviral agents are needed for the treatment of hepatitis B virus (HBV) infection because currently available drugs do not completely eradicate chronic HBV in patients. Phosphorylation dynamics of the...