Tatsunori Nishimura
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Explore the profile of Tatsunori Nishimura including associated specialties, affiliations and a list of published articles.
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21
Citations
386
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Recent Articles
11.
Konno M, Ishii H, Koseki J, Tanuma N, Nishida N, Kawamoto K, et al.
Regen Ther
. 2019 Jun;
1:63-71.
PMID: 31245442
The M2 isoform of pyruvate kinase, the final rate-limiting enzyme of aerobic glycolysis, is expressed during embryonic development. In contrast, the M1 isoform is expressed in differentiated cells due to...
12.
Tominaga K, Minato H, Murayama T, Sasahara A, Nishimura T, Kiyokawa E, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
116(2):625-630.
PMID: 30587593
Cancer stem-like cells (CSCs) are expanded in the CSC niche by increased frequency of symmetric cell divisions at the expense of asymmetric cell divisions. The symmetric division of CSCs is...
13.
Asai A, Koseki J, Konno M, Nishimura T, Gotoh N, Satoh T, et al.
Heliyon
. 2018 Dec;
4(12):e01021.
PMID: 30582043
Many anticancer drugs have serious adverse effects; therefore, it is necessary to target features specific to cancer cells to minimize the effects on healthy cells. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) was...
14.
Nishimura T, Nakata A, Chen X, Nishi K, Meguro-Horike M, Sasaki S, et al.
Oncogene
. 2018 Dec;
38(14):2464-2481.
PMID: 30532069
Tumor recurrence is attributable to cancer stem-like cells (CSCs), the metabolic mechanisms of which currently remain obscure. Here, we uncovered the critical role of folate-mediated one-carbon (1C) metabolism involving mitochondrial...
15.
Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, et al.
J Immunol
. 2018 Jan;
200(5):1839-1852.
PMID: 29378914
Macrophages in lungs can be classified into two subpopulations, alveolar macrophages (AMs) and interstitial macrophages (IMs), which reside in the alveolar and interstitial spaces, respectively. Accumulating evidence indicates the involvement...
16.
Hibiya S, Tsuchiya K, Hayashi R, Fukushima K, Horita N, Watanabe S, et al.
J Crohns Colitis
. 2017 Apr;
11(5):621-630.
PMID: 28453760
Background And Aims: Patients with ulcerative colitis [UC] are at an increased risk of developing colitis-associated cancer [CAC], suggesting that continuous inflammation in the colon promotes the transformation of colonic...
17.
Sasahara A, Tominaga K, Nishimura T, Yano M, Kiyokawa E, Noguchi M, et al.
Oncotarget
. 2017 Feb;
8(15):24869-24881.
PMID: 28206960
Cancer stem cells are thought to be responsible for tumor growth, recurrence, and resistance to conventional cancer therapy. However, it is still unclear how they are maintained in tumor tissues....
18.
Sasaki S, Baba T, Nishimura T, Hayakawa Y, Hashimoto S, Gotoh N, et al.
Cancer Lett
. 2016 May;
378(1):23-32.
PMID: 27177471
From a murine breast cancer cell line, 4T1, we established a subclone, 4T1.3, which consistently metastasizes to bone upon its injection into the mammary fat pad. 4T1.3 clone exhibited similar...
19.
Murayama T, Nakaoku T, Enari M, Nishimura T, Tominaga K, Nakata A, et al.
Cancer Res
. 2016 Feb;
76(4):974-83.
PMID: 26837769
The CD74-Neuregulin1 (NRG1) fusion gene was recently identified as novel driver of invasive mucinous adenocarcinoma, a malignant form of lung cancer. However, the function of the CD74-NRG1 fusion gene in...
20.
Kohsaka S, Hinohara K, Wang L, Nishimura T, Urushido M, Yachi K, et al.
Neuro Oncol
. 2014 Jan;
16(7):960-70.
PMID: 24470554
Background: Glioblastoma multiforme (GBM) is one of the most aggressive human tumors, and the establishment of an effective therapeutic reagent is a pressing priority. Recently, it has been shown that...