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Tate Owen

Explore the profile of Tate Owen including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 114
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Recent Articles
1.
Kamel A, Owen T, Cole I, Valencia T, Lee E
Drug Metab Dispos . 2023 Aug; 51(11):1536-1546. PMID: 37643880
RGLS4326 is a short oligonucleotide inhibitor of microRNA-17 (miR-17) that preferentially distributes to the kidney and displaces miR-17 from translationally active polysomes. Here, we present pharmacokinetics and absorption, distribution, metabolism,...
2.
Lee E, Valencia T, Allerson C, Schairer A, Flaten A, Yheskel M, et al.
Nat Commun . 2019 Sep; 10(1):4148. PMID: 31515477
Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in either PKD1 or PKD2 genes, is one of the most common human monogenetic disorders and the leading genetic cause of...
3.
Welink J, Xu Y, Yang E, Wilson A, Henderson N, Luo L, et al.
Bioanalysis . 2018 Nov; 10(22):1781-1801. PMID: 30488725
The 2018 12 Workshop on Recent Issues in Bioanalysis (12th WRIB) took place in Philadelphia, PA, USA on April 9-13, 2018 with an attendance of over 900 representatives from pharmaceutical/biopharmaceutical...
4.
Androsavich J, Sobczynski D, Liu X, Pandya S, Kaimal V, Owen T, et al.
Nucleic Acids Res . 2015 Sep; 44(2):e13. PMID: 26384419
Anti-miRNA (anti-miR) oligonucleotide drugs are being developed to inhibit overactive miRNAs linked to disease. To help facilitate the transition from concept to clinic, new research tools are required. Here we...
5.
Tantakitti F, Burk-Rafel J, Cheng F, Egnatchik R, Owen T, Hoffman M, et al.
Langmuir . 2012 Mar; 28(17):6950-9. PMID: 22435511
Self-assembled monolayers (SAMs) bearing pendant carbohydrate functionality are frequently employed to tailor glycan-specific bioactivity onto gold substrates. The resulting glycoSAMs are valuable for interrogating glycan-mediated biological interactions via surface analytical...
6.
Owen T, Butler A
Coord Chem Rev . 2011 May; 225(7-8):678-687. PMID: 21603255
This review covers selected surfactant ligands that undergo a change in aggregate morphology upon coordination of a metal ion, with a particular focus on coordination-induced micelle-to-vesicle transitions. The surfactants include...
7.
Owen T, Webb S, Butler A
Langmuir . 2008 Apr; 24(9):4999-5002. PMID: 18442226
The metal-induced micelle-to-vesicle phase change that the ferric complex of the microbially produced amphiphile, marinobactin E (M(E)), undergoes has been investigated by X-ray diffraction (XRD) and X-ray absorption spectroscopy (XAS)....
8.
Owen T, Pynn R, Hammouda B, Butler A
Langmuir . 2007 Jul; 23(18):9393-400. PMID: 17655261
Small-angle neutron scattering (SANS), cryogenic transmission electron microscopy (cryo-TEM), and dynamic light scattering (DLS) were used to study the metal-dependent phase behavior of microbially produced surfactants-marinobactins B, D, and E...
9.
Owen T, Pynn R, Martinez J, Butler A
Langmuir . 2005 Dec; 21(26):12109-14. PMID: 16342981
Small-angle neutron scattering (SANS) and dynamic light scattering (DLS) techniques have been applied to study the self-assembly processes of a microbially produced siderophore, marinobactin E (ME). ME is one of...