Taslim A Al-Hilal
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Explore the profile of Taslim A Al-Hilal including associated specialties, affiliations and a list of published articles.
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38
Citations
368
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Recent Articles
1.
Azam Z, Zhang X, Wahab R, Hasan M, Kang B, Hassan M, et al.
bioRxiv
. 2024 Aug;
PMID: 39211186
Detecting ovarian cancer (OC) early using existing biomarkers, e.g., cancer antigen 125 (CA125), is challenging due to its ubiquitous expression in many tissues. Doppel, a prion-like protein, expresses in male...
2.
Wahab R, Hasan M, Azam Z, Grippo P, Al-Hilal T
Adv Drug Deliv Rev
. 2023 Jul;
200:115027.
PMID: 37517779
The rising incidence and persistent thrombosis in multiple cancers including those that are immunosuppressive highlight the need for understanding the tumor coagulome system and its role beyond hemostatic complications. Immunotherapy...
3.
Kulkarni A, Gayathrinathan S, Nair S, Basu A, Al-Hilal T, Roy S
Cells
. 2022 Aug;
11(15).
PMID: 35954293
Annually, more than a million individuals are diagnosed with gastrointestinal (GI) cancers worldwide. With the advancements in radio- and chemotherapy and surgery, the survival rates for GI cancer patients have...
4.
Choi J, Zhang X, Hasan M, Karim M, Chung S, Alam F, et al.
Biomaterials
. 2022 Feb;
283:121423.
PMID: 35220018
Growth factors (GF) regulate normal development to cancer progression. GFs interact with extracellular matrix (ECM) biomolecules, such as heparin sulfate (HS) glycosaminoglycan (GAG), to enhance their stability and angiogenic signaling....
5.
Zhang X, Karim M, Hasan M, Hooper J, Wahab R, Roy S, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35158914
The microfluidic-based cancer-on-a-chip models work as a powerful tool to study the tumor microenvironment and its role in metastasis. The models recapitulate and systematically simplify the in vitro tumor microenvironment....
6.
Haque M, Rempert T, Al-Hilal T, Wang C, Bhushan A, Bishehsari F
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503294
Pancreatic Ductal Adenocarcinoma (PDAC) is an expeditiously fatal malignancy with a five-year survival rate of 6-8%. Conventional chemotherapeutics fail in many cases due to inadequate primary response and rapidly developing...
7.
Choi J, Lee N, Seo H, Chung S, Al-Hilal T, Park S, et al.
J Immunother Cancer
. 2021 Aug;
9(8).
PMID: 34341129
Purpose: Here, this study verifies that cancer-associated thrombosis (CAT) accelerates hypoxia, which is detrimental to the tumor immune microenvironment by limiting tumor perfusion. Therefore, we designed an oral anticoagulant therapy...
8.
Kadry H, Lagares D, Al-Hilal T
Methods Mol Biol
. 2021 May;
2299:227-236.
PMID: 34028747
Durotaxis is the phenomena of directed cell migration driven by gradients of extracellular matrix stiffness. Durotaxis has been recently involved in the development of fibrosis by promoting the recruitment of...
9.
Al-Hilal T, Hossain M, Alobaida A, Alam F, Keshavarz A, Nozik-Grayck E, et al.
J Control Release
. 2021 Apr;
334:237-247.
PMID: 33915222
ROCK, one of the downstream regulators of Rho, controls actomyosin cytoskeleton organization, stress fiber formation, smooth muscle contraction, and cell migration. ROCK plays an important role in the pathologies of...
10.
Shoyaib A, Alamri F, Biggers A, Karamyan S, Arumugam T, Ahsan F, et al.
Neuroscience
. 2021 Mar;
461:57-71.
PMID: 33667592
Treatments promoting post-stroke functional recovery continue to be an unmet therapeutic problem with physical rehabilitation being the most reproduced intervention in preclinical and clinical studies. Unfortunately, physiotherapy is typically effective...