Taryn A Miner
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Explore the profile of Taryn A Miner including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
196
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0
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Recent Articles
1.
Fashe M, Miner T, Collazo V, Grieco J, Fallon J, Jackson K, et al.
Drug Metab Dispos
. 2025 Mar;
53(2):100025.
PMID: 40023573
Cytochrome P450 (CYP) 3A4 is an essential drug-metabolizing enzyme in humans, which shows substantial interindividual variation in response to various intrinsic and extrinsic factors such as sex and pregnancy. In...
2.
Fashe M, Miner T, Fallon J, Schauer A, Sykes C, Smith P, et al.
Front Pharmacol
. 2023 Jul;
14():1218703.
PMID: 37475714
Pregnancy increases the clearance of CYP3A4 substrate drugs and pregnancy-related hormones (PRHs) induce hepatic CYP3A4 expression and metabolism. However, it remains unclear to what extent the magnitude of PRH-evoked changes...
3.
Ovchinnikova O, Treat L, Teelucksingh T, Clarke B, Miner T, Whitfield C, et al.
mBio
. 2023 May;
14(3):e0080023.
PMID: 37140436
Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics,...
4.
Fashe M, Fallon J, Miner T, Tiley J, Smith P, Lee C
Front Pharmacol
. 2022 Oct;
13:1004010.
PMID: 36210832
Pregnancy alters the disposition and exposure to multiple drugs indicated for pregnancy-related complications. Previous studies have shown that pregnancy-related hormones (PRHs) alter the expression and function of certain cytochrome P450s...
5.
Khatri R, Fallon J, Sykes C, Kulick N, Rementer R, Miner T, et al.
Front Pharmacol
. 2021 May;
12:655320.
PMID: 33995076
Pregnancy-related hormones (PRH) are recognized as important regulators of hepatic cytochrome P450 enzyme expression and function. However, the impact of PRH on the hepatic expression and function of uridine diphosphate...
6.
Quinn J, Weening E, Miner T, Miller V
J Bacteriol
. 2019 May;
201(16).
PMID: 31138630
PsaA, the subunit of the fimbria originally referred to as the "pH 6 antigen," is required for full virulence of during bubonic plague. The expression of is dependent upon specific...
7.
Walker K, Miner T, Palacios M, Trzilova D, Frederick D, Broberg C, et al.
mBio
. 2019 Mar;
10(2).
PMID: 30914502
The polysaccharide capsule is an essential virulence factor for in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidrug resistance....
8.
Palacios M, Miner T, Frederick D, Sepulveda V, Quinn J, Walker K, et al.
mBio
. 2018 Aug;
9(4).
PMID: 30087173
is widely recognized as a pathogen with a propensity for acquiring antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary tract infections [UTI], pneumonia, sepsis) and...