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Tarryn Willmer

Explore the profile of Tarryn Willmer including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 184
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Recent Articles
1.
Willmer T, Mabasa L, Sharma J, Muller C, Johnson R
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076974
Non-communicable diseases (NCDs) are the leading cause of death worldwide, with cardiovascular disease (CVD) accounting for half of all NCD-related deaths. The biological onset of CVD may occur long before...
2.
Mabasa L, Kotze A, Sangweni N, Willmer T, Gabuza K, Patel O, et al.
Biology (Basel) . 2025 Feb; 14(2). PMID: 40001874
While advancements in early detection and improved access to care have significantly enhanced breast cancer survival rates, the disease remains a significant global malignancy, constituting approximately 12.5% of all new...
3.
Abrahams Y, Willmer T, Patel O, Samodien E, Muller C, Windvogel S, et al.
Biochem Biophys Res Commun . 2023 Sep; 680:25-33. PMID: 37713959
Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia, hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the mechanisms...
4.
Dias S, Willmer T, Adam S, Pheiffer C
Front Clin Diabetes Healthc . 2023 Mar; 3:982665. PMID: 36992770
Diabetes in pregnancy is associated with adverse pregnancy outcomes and poses a serious threat to the health of mother and child. Although the pathophysiological mechanisms that underlie the association between...
5.
Pheiffer C, Dias S, Mendham A, Jack B, Willmer T, Eshibona N, et al.
Sci Rep . 2022 Nov; 12(1):18408. PMID: 36319747
The mechanisms that underlie exercise-induced adaptations in adipose tissue have not been elucidated, yet, accumulating studies suggest an important role for microRNAs (miRNAs). This study aimed to investigate miRNA expression...
6.
Willmer T, Oosthuizen A, Dias S, Mendham A, Goedecke J, Pheiffer C
Sci Rep . 2022 Jul; 12(1):11771. PMID: 35817784
We investigated gluteal (GSAT) and abdominal subcutaneous adipose tissue (ASAT) DNA methylation of FKBP5 in response to a 12-week intervention in African women with obesity, as well as the effect...
7.
Willmer T, Damerell V, Smyly S, Sims D, du Toit M, Ncube S, et al.
Am J Cancer Res . 2021 Dec; 11(11):5680-5700. PMID: 34873487
Sarcomas are diverse cancers of mesenchymal origin, with compromised clinical management caused by insufficient diagnostic biomarkers and limited treatment options. The transcription factor TBX3 is upregulated in a diverse range...
8.
Viraragavan A, Willmer T, Patel O, Basson A, Johnson R, Pheiffer C
Adipocyte . 2021 Feb; 10(1):108-118. PMID: 33570456
Increased visceral adipose tissue (VAT) is associated with metabolic dysfunction, while subcutaneous adipose tissue (SAT) is considered protective. The mechanisms underlying these differences are not fully elucidated. This study aimed...
9.
Pheiffer C, Willmer T, Dias S, Abrahams Y, Louw J, Goedecke J
Front Genet . 2020 Nov; 11:967. PMID: 33133129
Background: Metabolic risk varies according to body mass index (BMI), body fat distribution and ethnicity. In recent years, epigenetics, which reflect gene-environment interactions have attracted considerable interest as mechanisms that...
10.
Willmer T, Goedecke J, Dias S, Louw J, Pheiffer C
Clin Epigenetics . 2020 Sep; 12(1):141. PMID: 32958048
Background: Disruption of the hypothalamic-pituitary-adrenal (HPA) axis, a neuroendocrine system associated with the stress response, has been hypothesized to contribute to obesity development. This may be mediated through epigenetic modulation...