Taras Stasyk
Overview
Explore the profile of Taras Stasyk including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1261
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Recent Articles
1.
Stasyk T, Huber L
Methods Mol Biol
. 2022 Nov;
2596:97-104.
PMID: 36378433
Here, we describe a detailed step-by-step protocol for the detection of phosphoproteins in two-dimensional difference gel electrophoresis (2D-DIGE) gels. A standard 2D-DIGE protocol is combined with subsequent post-staining with phosphospecific...
2.
Cattelani C, Lesiak D, Liebscher G, Singer I, Stasyk T, Wallnofer M, et al.
Cells
. 2021 Oct;
10(10).
PMID: 34685691
Seizure threshold 2 (SZT2) is a component of the KICSTOR complex which, under catabolic conditions, functions as a negative regulator in the amino acid-sensing branch of mTORC1. Mutations in this...
3.
Nairz M, Bellmann-Weiler R, Ladstatter M, Schullner F, Zimmermann M, Koller A, et al.
Sci Rep
. 2021 Jan;
11(1):2261.
PMID: 33500503
The diagnosis of COVID-19 relies on the direct detection of SARS-CoV-2 RNA in respiratory specimens by RT-PCR. The pandemic spread of the disease caused an imbalance between demand and supply...
4.
Napolitano G, Di Malta C, Esposito A, de Araujo M, Pece S, Bertalot G, et al.
Nature
. 2020 Jul;
585(7826):597-602.
PMID: 32612235
The mechanistic target of rapamycin complex 1 (mTORC1) is a key metabolic hub that controls the cellular response to environmental cues by exerting its kinase activity on multiple substrates. However,...
5.
Lamberti G, de Smet C, Angelova M, Kremser L, Taub N, Herrmann C, et al.
FEBS Lett
. 2019 Aug;
594(1):31-42.
PMID: 31423582
Late endosomal/lysosomal adaptor and MAPK and mTOR activator (LAMTOR/Ragulator) is a scaffold protein complex that anchors and regulates multiprotein signaling units on late endosomes/lysosomes. To identify LAMTOR-modulated endolysosomal proteins, primary...
6.
Yordanov T, Hipolito V, Liebscher G, Vogel G, Stasyk T, Herrmann C, et al.
Traffic
. 2019 Jul;
20(9):674-696.
PMID: 31314175
Mechanisms that control lysosomal function are essential for cellular homeostasis. Lysosomes adapt in size and number to cellular needs but little is known about the underlying molecular mechanism. We demonstrate...
7.
Stasyk T, Huber L
Methods Mol Biol
. 2017 Oct;
1664:79-86.
PMID: 29019126
Here, we describe the detailed step-by-step protocol for detection of phosphoproteins in two-dimensional difference gel electrophoresis (DIGE) gels. A standard DIGE protocol is combined with subsequent post-staining with phosphospecific fluorescent...
8.
Filipek P, de Araujo M, Vogel G, de Smet C, Eberharter D, Rebsamen M, et al.
J Cell Biol
. 2017 Oct;
216(12):4199-4215.
PMID: 28993467
Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on...
9.
de Araujo M, Naschberger A, Furnrohr B, Stasyk T, Dunzendorfer-Matt T, Lechner S, et al.
Science
. 2017 Sep;
358(6361):377-381.
PMID: 28935770
The LAMTOR [late endosomal and lysosomal adaptor and MAPK (mitogen-activated protein kinase) and mTOR (mechanistic target of rapamycin) activator] complex, also known as "Ragulator," controls the activity of mTOR complex...
10.
Ranches G, Lukasser M, Schramek H, Ploner A, Stasyk T, Mayer G, et al.
Mol Ther Nucleic Acids
. 2017 Sep;
8:198-210.
PMID: 28918021
Chronic kidney disease (CKD) is a progressive pathological condition marked by a gradual loss of kidney function. Treatment of CKD is most effective when diagnosed at an early stage and...