Tara L Naylor
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Explore the profile of Tara L Naylor including associated specialties, affiliations and a list of published articles.
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9
Citations
1481
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Recent Articles
1.
Gao H, Korn J, Ferretti S, Monahan J, Wang Y, Singh M, et al.
Nat Med
. 2015 Oct;
21(11):1318-25.
PMID: 26479923
Profiling candidate therapeutics with limited cancer models during preclinical development hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous patient responses for patient-selection strategies. We established ∼1,000 patient-derived...
2.
Naylor T, Tang H, Ratsch B, Enns A, Loo A, Chen L, et al.
Cancer Res
. 2011 Feb;
71(7):2643-53.
PMID: 21324920
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) correlates with poor prognosis. The ABC subtype of DLBCL is associated with constitutive activation of the NF-κB pathway, and...
3.
Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues
Ma C, Quesnelle K, Sparano A, Rao S, Park M, Cohen M, et al.
Cancer Biol Ther
. 2009 Mar;
8(10):907-16.
PMID: 19276661
The Cub and Sushi Multiple Domains-1 (CSMD1) is a tumor suppressor gene on 8p23.2, where allelic loss is both frequent and associated with poor prognosis in head and neck squamous...
4.
Melchor L, Honrado E, Huang J, Alvarez S, Naylor T, Garcia M, et al.
Clin Cancer Res
. 2007 Dec;
13(24):7305-13.
PMID: 18094411
Purpose: Familial breast cancer represents 5% to 10% of all breast tumors. Mutations in the two known major breast cancer susceptibility genes, BRCA1 and BRCA2, account for a minority of...
5.
Zhang L, Huang J, Yang N, Greshock J, Megraw M, Giannakakis A, et al.
Proc Natl Acad Sci U S A
. 2006 Jun;
103(24):9136-41.
PMID: 16754881
MicroRNAs (miRNAs) are endogenous noncoding RNAs, which negatively regulate gene expression. To determine genomewide miRNA DNA copy number abnormalities in cancer, 283 known human miRNA genes were analyzed by high-resolution...
6.
Naylor T, Greshock J, Wang Y, Colligon T, Yu Q, Clemmer V, et al.
Breast Cancer Res
. 2006 Feb;
7(6):R1186-98.
PMID: 16457699
Introduction: Genomic aberrations in the form of subchromosomal DNA copy number changes are a hallmark of epithelial cancers, including breast cancer. The goal of the present study was to analyze...
7.
Jonsson G, Naylor T, Vallon-Christersson J, Staaf J, Huang J, Ward M, et al.
Cancer Res
. 2005 Sep;
65(17):7612-21.
PMID: 16140926
Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have shown that inherited and sporadic tumors progress along different somatic genetic pathways and...
8.
Margolin A, Greshock J, Naylor T, Mosse Y, Maris J, Bignell G, et al.
Bioinformatics
. 2005 May;
21(15):3308-11.
PMID: 15905276
Summary: This synopsis provides an overview of array-based comparative genomic hybridization data display, abstraction and analysis using CGHAnalyzer, a software suite, designed specifically for this purpose. CGHAnalyzer can be used...
9.
Greshock J, Naylor T, Margolin A, Diskin S, Cleaver S, Futreal P, et al.
Genome Res
. 2003 Dec;
14(1):179-87.
PMID: 14672980
Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology has tremendous potential for disease-gene discovery in cancer and developmental...