Tara I McIntyre
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Explore the profile of Tara I McIntyre including associated specialties, affiliations and a list of published articles.
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12
Citations
233
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Recent Articles
1.
McIntyre T, Valdez O, Kochhar N, Davidson B, Samad B, Qiu L, et al.
Cell
. 2025 Jan;
188(5):1265-1279.e18.
PMID: 39842437
Current efforts investigating parturition timing mechanisms have focused on the proximal triggers of labor onset generated in late pregnancy. By studying the delayed parturition phenotype of mice with uterine fibroblast...
2.
Siewiera J, McIntyre T, Cautivo K, Mahiddine K, Rideaux D, Molofsky A, et al.
Immunity
. 2023 Feb;
56(3):606-619.e7.
PMID: 36750100
Although mice normally enter labor when their ovaries stop producing progesterone (luteolysis), parturition can also be triggered in this species through uterus-intrinsic pathways potentially analogous to the ones that trigger...
3.
Farrington L, Callaway P, Vance H, Baskevitch K, Lutz E, Warrier L, et al.
PLoS Pathog
. 2020 Oct;
16(10):e1008997.
PMID: 33085728
Vγ9Vδ2 T cells rapidly respond to phosphoantigens produced by Plasmodium falciparum in an innate-like manner, without prior antigen exposure or processing. Vδ2 T cells have been shown to inhibit parasite...
4.
Odorizzi P, Jagannathan P, McIntyre T, Budker R, Prahl M, Auma A, et al.
Sci Transl Med
. 2018 Oct;
10(463).
PMID: 30333241
Malaria remains a significant cause of morbidity and mortality worldwide, particularly in infants and children. Some studies have reported that exposure to malaria antigens in utero results in the development...
5.
Boyle M, Jagannathan P, Bowen K, McIntyre T, Vance H, Farrington L, et al.
Front Immunol
. 2017 Nov;
8:1329.
PMID: 29097996
Cytokine-producing CD4 T cells have important roles in immunity against malaria. However, the factors influencing functional differentiation of specific CD4 T cells in naturally exposed children are not well understood....
6.
Jagannathan P, Lutwama F, Boyle M, Nankya F, Farrington L, McIntyre T, et al.
Sci Rep
. 2017 Sep;
7(1):11487.
PMID: 28904345
Vδ2 γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection in naïve adults, but are lost and become dysfunctional among children repeatedly exposed to...
7.
Prahl M, Jagannathan P, McIntyre T, Auma A, Wamala S, Nalubega M, et al.
Open Forum Infect Dis
. 2017 May;
4(1):ofx022.
PMID: 28480292
Sex differences in the immune response and in infectious disease susceptibility have been well described, although the mechanisms underlying these differences remain incompletely understood. We evaluated the frequency of cord...
8.
Prahl M, Jagannathan P, McIntyre T, Auma A, Farrington L, Wamala S, et al.
Malar J
. 2016 Oct;
15(1):497.
PMID: 27717402
Background: In malaria-endemic areas, the first exposure to malaria antigens often occurs in utero when the fetal immune system is poised towards the development of tolerance. Children exposed to placental...
9.
Fontana M, Baccarella A, Craft J, Boyle M, McIntyre T, Wood M, et al.
PLoS One
. 2016 Sep;
11(9):e0162132.
PMID: 27583554
In humans, immunity to Plasmodium sp. generally takes the form of protection from symptomatic malaria (i.e., 'clinical immunity') rather than infection ('sterilizing immunity'). In contrast, mice infected with Plasmodium develop...
10.
Jagannathan P, Bowen K, Nankya F, McIntyre T, Auma A, Wamala S, et al.
J Infect Dis
. 2016 Apr;
214(2):329-38.
PMID: 27067196
Background: Experimental inoculation of viable Plasmodium falciparum sporozoites administered with chemoprevention targeting blood-stage parasites results in protective immunity. It is unclear whether chemoprevention similarly enhances immunity following natural exposure to...