Tara G Vrooman
Overview
Explore the profile of Tara G Vrooman including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
27
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0
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Recent Articles
1.
Ye J, Qin S, Hughson A, Hannon G, Vrooman T, Lesch M, et al.
Cancers (Basel)
. 2025 Jan;
17(2).
PMID: 39857986
: Pancreatic ductal adenocarcinoma (PDAC), expecting to be the second leading cause of cancer deaths by 2030, resists immune checkpoint therapies due to its immunosuppressive tumor microenvironment (TME). Leukemia inhibitory...
2.
Hughson A, Hannon G, Salama N, Vrooman T, Stockwell C, Mills B, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(4):102350.
PMID: 39469666
Pronounced T cell exhaustion characterizes immunosuppressive tumors, with the tumor microenvironment (TME) employing multiple mechanisms to elicit this suppression. Traditional immunotherapies, such as immune checkpoint blockade, often fail due to...
3.
Hughson A, Hannon G, Salama N, Vrooman T, Stockwell C, Mills B, et al.
bioRxiv
. 2023 Nov;
PMID: 37961513
Statement Of Significance: This study demonstrates the use of a novel combination treatment consisting of radiation and immunotherapy in murine pancreatic tumors. This treatment could effectively treat local and metastatic...
4.
Ye J, Gavras N, Keeley D, Hughson A, Hannon G, Vrooman T, et al.
J Immunother Cancer
. 2023 May;
11(5).
PMID: 37142292
Background: Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of...
5.
Ye J, Mills B, Qin S, Garrett-Larsen J, Murphy J, Uccello T, et al.
J Immunother Cancer
. 2022 Jul;
10(7).
PMID: 35851308
Background: Stereotactic body radiotherapy (SBRT) has been increasingly used as adjuvant therapy in pancreatic ductal adenocarcinoma (PDAC), and induces immunogenic cell death, which leads to the release of tumor antigen...