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Tara E Crawford Parks

Explore the profile of Tara E Crawford Parks including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 105
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Recent Articles
1.
Almasi S, Crawford Parks T, Ravel-Chapuis A, Mackenzie A, Cote J, Cowan K, et al.
Cell Oncol (Dordr) . 2021 Apr; 44(4):851-870. PMID: 33899158
Purpose: Recent work has highlighted the therapeutic potential of targeting autophagy to modulate cell survival in a variety of diseases including cancer. Recently, we found that the RNA-binding protein Staufen1...
2.
Marcellus K, Crawford Parks T, Almasi S, Jasmin B
BMC Cancer . 2021 Feb; 21(1):120. PMID: 33541283
Background: Prostate cancer is one of the most common malignant cancers with the second highest global rate of mortality in men. During the early stages of disease progression, tumour growth...
3.
Crawford Parks T, Marcellus K, Peladeau C, Jasmin B, Ravel-Chapuis A
Hum Mol Genet . 2020 Jun; 29(13):2185-2199. PMID: 32504084
In myotonic dystrophy type 1 (DM1), the CUG expansion (CUGexp) in the 3' untranslated region of the dystrophia myotonica protein kinase messenger ribonucleic acid affects the homeostasis of ribonucleic acid-binding...
4.
Crawford Parks T, Ravel-Chapuis A, Bondy-Chorney E, Renaud J, Cote J, Jasmin B
Hum Mol Genet . 2017 Apr; 26(10):1821-1838. PMID: 28369467
Converging lines of evidence have now highlighted the key role for post-transcriptional regulation in the neuromuscular system. In particular, several RNA-binding proteins are known to be misregulated in neuromuscular disorders...
5.
Crawford Parks T, Marcellus K, Langill J, Ravel-Chapuis A, Michaud J, Cowan K, et al.
Sci Rep . 2017 Feb; 7:42342. PMID: 28211476
Rhabdomyosarcoma is the most common soft tissue sarcoma in children and young adults. Rhabdomyosarcomas are skeletal muscle-like tumours that typically arise in muscle beds, and express key myogenic regulatory factors....
6.
Bondy-Chorney E, Crawford Parks T, Ravel-Chapuis A, Jasmin B, Cote J
Rare Dis . 2016 Oct; 4(1):e1225644. PMID: 27695661
In a recent issue of , we reported that the double-stranded RNA-binding protein, Staufen1, functions as a disease modifier in the neuromuscular disorder Myotonic Dystrophy Type I (DM1). In this...
7.
Ravel-Chapuis A, Klein Gunnewiek A, Belanger G, Crawford Parks T, Cote J, Jasmin B
Mol Biol Cell . 2016 Apr; 27(11):1728-39. PMID: 27030674
Myotonic dystrophy (DM1) is caused by an expansion of CUG repeats (CUG(exp)) in the DMPK mRNA 3'UTR. CUG(exp)-containing mRNAs become toxic to cells by misregulating RNA-binding proteins. Here we investigated...
8.
Bondy-Chorney E, Crawford Parks T, Ravel-Chapuis A, Klinck R, Rocheleau L, Pelchat M, et al.
PLoS Genet . 2016 Jan; 12(1):e1005827. PMID: 26824521
Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder caused by an expansion of CUG repeats in the 3' UTR of the DMPK gene. The CUG repeats form aggregates of...
9.
Peladeau C, Ahmed A, Amirouche A, Crawford Parks T, Bronicki L, Ljubicic V, et al.
Hum Mol Genet . 2015 Oct; 25(1):24-43. PMID: 26494902
Upregulation of utrophin A is an attractive therapeutic strategy for treating Duchenne muscular dystrophy (DMD). Over the years, several studies revealed that utrophin A is regulated by multiple transcriptional and...