Kyle N Cowan
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Explore the profile of Kyle N Cowan including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
546
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0
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Recent Articles
1.
Freeman E, Langlois S, Leyba M, Ammar T, Leger Z, McMillan H, et al.
Skelet Muscle
. 2024 Apr;
14(1):8.
PMID: 38671506
Background: Duchenne muscular dystrophy (DMD) is associated with impaired muscle regeneration, progressive muscle weakness, damage, and wasting. While the cause of DMD is an X-linked loss of function mutation in...
2.
Hung J, Langlois S, Wiebe M, Wild B, Barre-Dunn J, Cowan K
J Pediatr Surg
. 2024 Feb;
59(5):839-846.
PMID: 38365473
Background: Pulmonary vascular disease (PVD) complicated with pulmonary hypertension (PH) is a leading cause of mortality in congenital diaphragmatic hernia (CDH). Unfortunately, CDH patients are often resistant to PH therapy....
3.
Almasi S, SarmastiEmami S, Baird S, Ning Z, Figeys D, Cote J, et al.
Cell Mol Life Sci
. 2023 Oct;
80(11):328.
PMID: 37847286
Elevated mitochondrial metabolism promotes tumorigenesis of Embryonal Rhabdomyosarcomas (ERMS). Accordingly, targeting oxidative phosphorylation (OXPHOS) could represent a therapeutic strategy for ERMS. We previously demonstrated that genetic reduction of Staufen1 (STAU1)...
4.
Langlois S, St-Pierre M, Holland S, Xiang X, Freeman E, Mohamed H, et al.
J Cancer
. 2023 Apr;
14(5):689-706.
PMID: 37056395
Pannexin 1 (PANX1) is expressed in many tissue types including tissues of neural origin. Neuroblastoma (NB) is a neural crest-derived malignancy mainly occurring in children. The majority of NB patients...
5.
Edwards M, Liy-Wong C, Byrne A, Cowan K, Ahmet A
Can J Diabetes
. 2022 Sep;
47(2):190-192.
PMID: 36137870
No abstract available.
6.
Freeman E, Langlois S, Scott K, Ravel-Chapuis A, Jasmin B, Cowan K
J Cell Physiol
. 2022 Aug;
237(10):3944-3959.
PMID: 35938715
The development and regeneration of skeletal muscle are mediated by satellite cells (SCs), which ensure the efficient formation of myofibers while repopulating the niche that allows muscle repair following injuries....
7.
Cerron-Vela C, Youssef F, Cowan K, Davila J
Radiol Case Rep
. 2022 Mar;
17(5):1558-1562.
PMID: 35282320
Horseshoe lung (HL) is a rare congenital anomaly that has been classically associated with Scimitar syndrome. Very few cases have been described in the context of the VACTERL spectrum. We...
8.
Xiang X, Hoang H, Gilchrist V, Langlois S, Alain T, Cowan K
Oncogenesis
. 2022 Feb;
11(1):9.
PMID: 35194046
Rhabdomyosarcoma (RMS) is a deadly cancer of skeletal muscle origin. Pannexin 1 (PANX1) is down-regulated in RMS and increasing its levels drastically inhibits RMS progression. PANX1 upregulation thus represents a...
9.
Mohamed H, Pastor M, Langlois S, Cowan K
J Pediatr Surg
. 2022 Jan;
57(5):866-870.
PMID: 35086681
Background: Adequate tissue biopsy is essential for diagnosis and risk stratification of neuroblastoma (NB). Historically, NB diagnosis has relied on tissue obtained via surgical biopsy. However, core needle biopsy may...
10.
Almasi S, Crawford Parks T, Ravel-Chapuis A, Mackenzie A, Cote J, Cowan K, et al.
Cell Oncol (Dordr)
. 2021 Apr;
44(4):851-870.
PMID: 33899158
Purpose: Recent work has highlighted the therapeutic potential of targeting autophagy to modulate cell survival in a variety of diseases including cancer. Recently, we found that the RNA-binding protein Staufen1...