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Tanzeer Kaur

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Articles 36
Citations 232
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Recent Articles
1.
Singh R, Kaur N, Sharma S, Dhingra N, Kaur T
Mol Divers . 2025 Jan; PMID: 39873884
Alzheimer's disease (AD) is a degenerative neurological disorder defined by the formation of β-amyloid (Aβ) plaques and neurofibrillary tangles within the brain. Current pharmacological treatments for AD only provide symptomatic...
2.
Sharma S, Rana P, Chadha V, Dhingra N, Kaur T
Eur Biophys J . 2024 Nov; 53(7-8):447-464. PMID: 39488633
Neuropathic pain (NP) is characterized by hyperalgesia, allodynia, and spontaneous pain. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel involved in neuronal hyperexcitability, has emerged as an important target for the drug development...
3.
Kaur T, Sidana P, Kaur N, Choubey V, Kaasik A
Inflammopharmacology . 2024 Aug; 32(5):2801-2820. PMID: 39136812
Parkinson's disease (PD) is an age-related chronic neurological condition characterized by progressive degeneration of dopaminergic neurons and the presence of Lewy bodies, primarily composed of alpha-synuclein and ubiquitin. The pathophysiology...
4.
Kaur N, Singh R, Dhingra N, Kaur T
Biochem Pharmacol . 2024 Jun; 226:116343. PMID: 38852645
The abnormal accumulation of fibrillar α-synuclein in the substantia nigra contributes to Parkinson's disease (PD). Chemical chaperones like 4-phenyl butyric acid (4PBA) show neuroprotective potential, but high doses are required....
5.
Singh R, Kaur N, Dhingra N, Kaur T
Neurochem Int . 2024 May; 177:105762. PMID: 38723901
Linalool is a neuroprotective monoterpene found in essential oils from aromatic plants. Linalool's effectiveness in AD animal models has been established previously, but its mechanisms of action remain unclear. Therefore,...
6.
Singh R, Kaur N, Choubey V, Dhingra N, Kaur T
Brain Res . 2023 Dec; 1826:148742. PMID: 38159591
The Endoplasmic reticulum (ER), a critical cellular organelle, maintains cellular homeostasis by regulating calcium levels and orchestrating essential functions such as protein synthesis, folding, and lipid production. A pivotal aspect...
7.
Kaur J, Rana P, Matta T, Sodhi R, Pathania K, Pawar S, et al.
Inflammopharmacology . 2023 Oct; 32(1):603-627. PMID: 37847473
Background: Morbidity and mortality rates associated with acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are high (30-40%). Nuclear factor-kappa B (NF-κB) is a transcription factor, associated with transcription of numerous...
8.
Kaur N, Singh R, Das A, Agarwal S, Dhingra N, Kaur T
Appl Biochem Biotechnol . 2023 Jul; 196(4):2086-2109. PMID: 37466885
Aggregated α-synuclein (α-syn) present inside small cytoplasmic inclusions in the substantia nigra region marks the major pathological hallmark of Parkinson's disease (PD) and makes it an attractive target for the...
9.
Bhardwaj A, Bhardwaj R, Saini A, Dhawan D, Kaur T
Cell Mol Neurobiol . 2022 Aug; 43(4):1619-1635. PMID: 36002608
Excessive activation of α-amino-3-hydroxy-5-methyl-4-isoxazole propoinic acid (AMPA) receptors instigates excitotoxicity via enhanced calcium influx in the neurons thus inciting deleterious consequences. Additionally, Endoplasmic Reticulum (ER) is pivotal in maintaining the...
10.
Bhardwaj R, Bhardwaj A, Dhawan D, Tandon C, Kaur T
Life Sci . 2022 Jul; 305:120786. PMID: 35809664
Aim: Urinary glycoproteins such as Tamm Horsfall Protein (THP) and Osteopontin (OPN) are well established key regulators of renal stone formation. Additionally, recent revelations have highlighted the influence of Endoplasmic...