Tanos C C Franca
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Explore the profile of Tanos C C Franca including associated specialties, affiliations and a list of published articles.
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64
Citations
381
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Recent Articles
11.
Ribeiro R, Botelho F, Pinto A, La Torre A, Almeida J, LaPlante S, et al.
J Mol Model
. 2023 May;
29(6):183.
PMID: 37212923
Context: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 infection and responsible for millions of victims worldwide, remains a significant threat to public health....
12.
Ali Z, Cardoza J, Basak S, Narsaria U, Singh V, Isaac S, et al.
J Biomol Struct Dyn
. 2023 Feb;
41(22):13348-13367.
PMID: 36744449
The COVID-19 pandemic caused by SARS-CoV-2 virus has created a global damage and has exposed the vulnerable side of scientific research towards novel diseases. The intensity of the pandemic is...
13.
Franca T, Botelho F, Drummond M, LaPlante S
ACS Omega
. 2022 Sep;
7(36):32805-32815.
PMID: 36120038
Recently, we reported a library of 82 compounds, selected from different databanks through virtual screening and docking studies, and pointed to 6 among them as potential repurposed dual binders to...
14.
Botelho F, Nepovimova E, Kamil K, Franca T
J Mol Model
. 2022 Sep;
28(10):315.
PMID: 36104501
In the present work, a library of 239 frentizole derivatives formerly synthesized by our research group were virtually screened on the FRB domain of mTOR in a search of potential...
15.
Goncalves M, Goncalves A, Franca T, Santana M, da Cunha E, Ramalho T
J Chem Theory Comput
. 2022 Sep;
18(10):5810-5818.
PMID: 36103405
Wavelets are mathematical tools used to decompose and represent another function described in the time domain, allowing the study of each component of the original function with a scale-compatible resolution....
16.
Bondar D, Kapitanov I, Pulkrabkova L, Soukup O, Jun D, Botelho F, et al.
Chem Biol Interact
. 2022 Aug;
365:110078.
PMID: 35940282
The problem of the efficient treatment of acute organophosphorus (OP) poisoning needs more efforts in the development of a versatile antidote, applicable for treatment of the injuries of both peripheral...
17.
Santos M, Botelho F, Goncalves A, Kitagawa D, Borges C, Carvalho-Silva T, et al.
Arch Toxicol
. 2022 Jun;
96(9):2559-2572.
PMID: 35666269
The misuse of novichok agents in assassination attempts has been reported in the international media since 2018. These relatively new class of neurotoxic agents is claimed to be more toxic...
18.
Santos M, Botelho F, Goncalves A, Kuca K, Nepovimova E, Cavalcante S, et al.
Food Chem Toxicol
. 2022 Apr;
165:113084.
PMID: 35489467
The nerve agents of the A-series are relatively recent chemical weapons with no antidote available yet. Once inside the human body, those chemicals act similarly to the classic nerve agents,...
19.
Farahani M, Franca T, Alapour S, Shahout F, Boulon R, Iddir M, et al.
ChemMedChem
. 2022 Mar;
17(10):e202200092.
PMID: 35298873
A focused drug repurposing approach is described where an FDA-approved drug is rationally selected for biological testing based on structural similarities to a fragment compound found to bind a target...
20.
Garcia D, Souza F, Guimaraes A, Valis M, Pavelek Z, Kuca K, et al.
Pharmaceuticals (Basel)
. 2021 Oct;
14(10).
PMID: 34681251
Continuing the work developed by our research group, in the present manuscript, we performed a theoretical study of 10 new structures derived from the antivirals cidofovir and ribavirin, as inhibitor...