Tanja Ilmarinen
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Explore the profile of Tanja Ilmarinen including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
682
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Recent Articles
1.
Viheriala T, Hongisto H, Saari L, Oksanen M, Ilmarinen T, Vaaramaki S, et al.
J Ophthalmol
. 2024 Sep;
2024:6939920.
PMID: 39347541
Pseudoxanthoma elasticum (PXE) is a rare metabolic disease with autosomal recessive inheritance. The manifestation in PXE is represented by retinal complications, pseudoxanthomas of the skin folding areas, and arterial calcification....
2.
Kauppila M, Vattulainen M, Ihalainen T, Moro A, Ilmarinen T, Skottman H
Ocul Surf
. 2024 Jun;
34:50-59.
PMID: 38945477
Purpose: Human donor corneas are an essential control tissue for corneal research. We utilized whole mount immunofluorescence (WM-IF) to evaluate how the storage affects the tissue integrity and putative limbal...
3.
Vattulainen M, Smits J, Arts J, Lima Cunha D, Ilmarinen T, Skottman H, et al.
Stem Cell Reports
. 2024 Jun;
19(7):1010-1023.
PMID: 38942029
A comprehensive understanding of the human pluripotent stem cell (hPSC) differentiation process stands as a prerequisite for the development of hPSC-based therapeutics. In this study, single-cell RNA sequencing (scRNA-seq) was...
4.
Gronroos P, Moro A, Puistola P, Hopia K, Huuskonen M, Viheriala T, et al.
Stem Cell Res Ther
. 2024 Mar;
15(1):81.
PMID: 38486306
Background: Human corneal endothelial cells lack regenerative capacity through cell division in vivo. Consequently, in the case of trauma or dystrophy, the only available treatment modality is corneal tissue or...
5.
Ilmarinen T, Vattulainen M, Kandhavelu J, Bremond-Gignac D, Aberdam D, Skottman H
Stem Cells
. 2023 Aug;
41(12):1133-1141.
PMID: 37632794
Congenital aniridia is caused by heterozygous mutations on the PAX6 gene leading to reduced amount of PAX6 protein (haploinsufficiency), abnormal eye development, and aniridia-associated keratopathy (AAK). This progressive corneal opacification...
6.
Kauppila M, Moro A, Valle-Delgado J, Ihalainen T, Sukki L, Puistola P, et al.
Adv Healthc Mater
. 2023 Jul;
12(29):e2301396.
PMID: 37449943
A functional limbal epithelial stem cells (LSC) niche is a vital element in the regular renewal of the corneal epithelium by LSCs and maintenance of good vision. However, little is...
7.
Viheriala T, Hongisto H, Sorvari J, Skottman H, Nymark S, Ilmarinen T
Stem Cell Res Ther
. 2022 Jan;
13(1):30.
PMID: 35073969
Background: Transplantation of human pluripotent stem cell-derived retinal pigment epithelium (RPE) is an urgently needed treatment for the cure of degenerative diseases of the retina. The transplanted cells must tolerate...
8.
Vattulainen M, Ilmarinen T, Viheriala T, Jokinen V, Skottman H
Stem Cell Res Ther
. 2021 Dec;
12(1):609.
PMID: 34930437
Background: Differentiation of functional limbal stem cells (LSCs) from human pluripotent stem cells (hPSCs) is an important objective which can provide novel treatment solutions for patients suffering from limbal stem...
9.
Liu Z, Ilmarinen T, Tan G, Hongisto H, Wong E, Tsai A, et al.
Stem Cell Res Ther
. 2021 Jul;
12(1):423.
PMID: 34315534
Background: Human pluripotent stem cells (hPSCs) provide a promising cell source for retinal cell replacement therapy but often lack standardized cell production and live-cell shipment logistics as well as rigorous...
10.
Gronroos P, Ilmarinen T, Skottman H
Cells
. 2021 Feb;
10(2).
PMID: 33562615
The most crucial function of corneal endothelial cells (CEnCs) is to maintain optical transparency by transporting excess fluid out of stroma. Unfortunately, CEnCs are not able to proliferate in vivo...