Tanima SenGupta
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Explore the profile of Tanima SenGupta including associated specialties, affiliations and a list of published articles.
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19
Citations
646
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Recent Articles
1.
Zouraris D, Mavrogiorgis A, Tsoumanis A, Saarimaki L, Del Giudice G, Federico A, et al.
Comput Struct Biotechnol J
. 2025 Jan;
29:13-28.
PMID: 39872495
The CompSafeNano project, a Research and Innovation Staff Exchange (RISE) project funded under the European Union's Horizon 2020 program, aims to advance the safety and innovation potential of nanomaterials (NMs)...
2.
Perez-Mato M, Dopico-Lopez A, Akkoc Y, Lopez-Amoedo S, Correa-Paz C, Candamo-Lourido M, et al.
iScience
. 2024 Nov;
27(11):111108.
PMID: 39524351
The blood enzyme glutamate-oxaloacetate transaminase (GOT) has been postulated as an effective therapeutic to protect the brain during stroke. To demonstrate its potential clinical utility, a new human recombinant form...
3.
Turconi G, Alam F, SenGupta T, Pirnes-Karhu S, Olfat S, Schmidt M, et al.
Heliyon
. 2024 Aug;
10(14):e34355.
PMID: 39108921
Parkinson's disease (PD) is associated with a reduction in 26/20S proteasome and mitochondrial function and depletion of dopamine. Activation of mitochondrial function with the NAD precursor nicotinamide riboside (NR) is...
4.
Serafini M, Sepehri S, Midali M, Stinckens M, Biesiekierska M, Wolniakowska A, et al.
Arch Toxicol
. 2024 Mar;
98(5):1271-1295.
PMID: 38480536
Adult neurotoxicity (ANT) and developmental neurotoxicity (DNT) assessments aim to understand the adverse effects and underlying mechanisms of toxicants on the human nervous system. In recent years, there has been...
5.
Sleiman A, Lalanne K, Vianna F, Perrot Y, Richaud M, SenGupta T, et al.
Biology (Basel)
. 2023 Jun;
12(6).
PMID: 37372124
Fifty percent of all patients with cancer worldwide require radiotherapy. In the case of brain tumors, despite the improvement in the precision of radiation delivery with proton therapy, studies have...
6.
SenGupta T, Lefol Y, Lirussi L, Suaste V, Luders T, Gupta S, et al.
Aging (Albany NY)
. 2022 Nov;
14(21):8661-8687.
PMID: 36367773
There is accumulating evidence that interfering with the basic aging mechanisms can enhance healthy longevity. The interventional/therapeutic strategies targeting multiple aging hallmarks could be more effective than targeting one hallmark....
7.
Naranjo-Galindo F, Ai R, Fang E, Nilsen H, SenGupta T
Front Aging
. 2022 Jul;
3:916118.
PMID: 35821838
Since its introduction as a genetic model organism, has yielded insights into the causes of aging. In addition, it has provided a molecular understanding of mechanisms of neurodegeneration, one of...
8.
Palikaras K, SenGupta T, Nilsen H, Tavernarakis N
STAR Protoc
. 2022 Apr;
3(2):101264.
PMID: 35403008
Transgenic that expresses the full-length wild-type human α-synuclein in dopaminergic neurons provides a well-established Parkinson's disease (PD) nematode model. Here, we present a detailed protocol to monitor and dissect the...
9.
SenGupta T, Palikaras K, Esbensen Y, Konstantinidis G, Galindo F, Achanta K, et al.
Cell Rep
. 2021 Sep;
36(10):109668.
PMID: 34496255
Aging, genomic stress, and mitochondrial dysfunction are risk factors for neurodegenerative pathologies, such as Parkinson disease (PD). Although genomic instability is associated with aging and mitochondrial impairment, the underlying mechanisms...
10.
Gupta S, You P, SenGupta T, Nilsen H, Sharma K
Biology (Basel)
. 2021 Mar;
10(2).
PMID: 33669593
Genomic integrity is maintained by DNA repair and the DNA damage response (DDR). Defects in certain DNA repair genes give rise to many rare progressive neurodegenerative diseases (NDDs), such as...