Tang K Tang
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Explore the profile of Tang K Tang including associated specialties, affiliations and a list of published articles.
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39
Citations
1118
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Recent Articles
1.
Guguin J, Chen T, Cuinat S, Besson A, Bertiaux E, Boutaud L, et al.
PLoS Genet
. 2024 Dec;
20(12):e1011517.
PMID: 39680576
Taybi-Linder syndrome (TALS) is a rare autosomal recessive disorder characterized by severe microcephaly with abnormal gyral pattern, severe growth retardation and bone abnormalities. It is caused by pathogenic variants in...
2.
Wang Y, Chen S, Gu D, Yeh Y, Tsai J, Yang K, et al.
J Biomed Sci
. 2024 Apr;
31(1):35.
PMID: 38594661
No abstract available.
3.
Chang C, Chen T, Tang T
Methods Cell Biol
. 2023 Mar;
175:235-249.
PMID: 36967143
Joubert syndrome (JS) is an autosomal recessive ciliopathy that mainly affects the morphogenesis of the cerebellum and brain stem. To date, mutations in at least 39 genes have been identified...
4.
Wang Y, Chen S, Gu D, Yeh Y, Tsai J, Yang K, et al.
J Biomed Sci
. 2022 Apr;
29(1):24.
PMID: 35365182
Background: Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial-mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the...
5.
An H, Kuo H, Tang T
Front Cell Dev Biol
. 2022 Mar;
10:830432.
PMID: 35309908
The centrosome is composed of a pair of centrioles and serves as the major microtubule-organizing center (MTOC) in cells. Centrosome dysfunction has been linked to autosomal recessive primary microcephaly (MCPH),...
6.
Chang C, Chen T, Lu I, Li R, Tsai J, Lin P, et al.
Genes Dev
. 2021 Oct;
35(21-22):1445-1460.
PMID: 34711653
Joubert syndrome (JS) is a recessive ciliopathy in which all affected individuals have congenital cerebellar vermis hypoplasia. Here, we report that CEP120, a JS-associated protein involved in centriole biogenesis and...
7.
Chou E, Tang T
Cells
. 2021 Jul;
10(6).
PMID: 34207628
Autosomal recessive primary microcephaly () is a complex neurodevelopmental disorder characterized by a small brain size with mild to moderate intellectual disability. We previously demonstrated that human microcephaly played an...
8.
Chen T, Huang B, Tang T, Chao Y, Xiao X, Lee P, et al.
Cell Death Differ
. 2021 Jan;
28(6):1865-1879.
PMID: 33462409
The DNA-PK maintains cell survival when DNA damage occurs. In addition, aberrant activation of the DNA-PK induces centrosome amplification, suggesting additional roles for this kinase. Here, we showed that the...
9.
Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly
Lin Y, Lee Y, Li S, Tang T
J Cell Sci
. 2020 Jun;
133(12).
PMID: 32501282
Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by small brain size with mental retardation. (also known as ), a known microcephaly-associated gene, plays a key role in centriole biogenesis....
10.
Tsai J, Hsu W, Liu J, Chang C, Tang T
Sci Rep
. 2020 Jan;
10(1):1265.
PMID: 31965052
An amendment to this paper has been published and can be accessed via a link at the top of the paper.