Taketoshi Kajimoto
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Explore the profile of Taketoshi Kajimoto including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
837
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Recent Articles
1.
Ueda Y, Kiyonaka S, Selfors L, Inoue K, Harada H, Doura T, et al.
Nat Cell Biol
. 2025 Feb;
27(3):530-543.
PMID: 39984655
Intratumour heterogeneity represents the hierarchical integration of genetic, phenotypic and microenvironmental heterogeneity. Although single-cell sequencing has clarified genetic and phenotypic variability, the heterogeneity of nongenetic, microenvironmental factors remains elusive. Here,...
2.
Ishii T, Kajimoto T, Kikkawa S, Narasaki S, Noguchi S, Imamura S, et al.
Eur J Pharmacol
. 2024 Oct;
984:177036.
PMID: 39368603
Calphostin C (Cal-C) is a protein kinase C (PKC) inhibitor that binds to its C1 domain. The aim of the present study was to elucidate the action of Cal-C in...
3.
Nishida S, Matovelo S, Kajimoto T, Nakamura S, Okada T
Commun Biol
. 2024 Sep;
7(1):1182.
PMID: 39300315
The insulin-like growth factor II/mannose 6-phosphate (IGF-II/M6P) receptor is a multifunctional glycoprotein not only play roles in IGF-II degradation and pro-TGFβ activation but binding to and transport M6P-bearing lysosomal enzymes...
4.
Nishida S, Matovelo S, Kajimoto T, Nakamura S, Okada T
Genes Cells
. 2024 Jan;
29(3):207-216.
PMID: 38163647
α-Synuclein (α-Syn)-positive intracellular fibrillar protein deposits, known as Lewy bodies, are thought to be involved in the pathogenesis of Parkinson's disease (PD). Although recent lines of evidence suggested that extracellular...
5.
Noguchi S, Kajimoto T, Kumamoto T, Shingai M, Narasaki S, Urabe T, et al.
Front Pharmacol
. 2023 Nov;
14:1284586.
PMID: 38026993
In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C (PKC) translocation. Various PKCs fused with green fluorescent protein (PKC-GFP) or...
6.
Jung H, Fattet L, Tsai J, Kajimoto T, Chang Q, Newton A, et al.
Nat Cell Biol
. 2023 Aug;
25(9):1385.
PMID: 37580389
No abstract available.
7.
Narasaki S, Noguchi S, Urabe T, Harada K, Hide I, Tanaka S, et al.
Eur J Pharmacol
. 2023 May;
955:175806.
PMID: 37230321
Propofol is widely used for general anesthesia and sedation; however, the mechanisms of its anesthetic and adverse effects are not fully understood. We have previously shown that propofol activates protein...
8.
Okada T, Nishida S, Zhang L, Ibrahim Mohamed N, Wang T, Ijuin T, et al.
iScience
. 2021 Nov;
24(11):103351.
PMID: 34805799
The importance of the G-protein βγ subunits in the regulation of cargo transport from the -Golgi network (TGN) to the plasma membrane (PM) is well accepted; however, the molecular mechanism...
9.
Kajimoto T, Nakamura S
Bio Protoc
. 2021 Sep;
8(24):e3111.
PMID: 34532553
Function of extracellular vesicles such as exosomes and microvesicles is determined by their wide ranges of cargoes inside them. Even in the pure exosomes or microvesicles the cargo contents are...
10.
Matovelo S, Zhang L, Ibrahim Mohamed N, Kajimoto T, Ijuin T, Okada T, et al.
Kobe J Med Sci
. 2021 Jan;
66(3):E94-E101.
PMID: 33431782
Macropinocytosis is a highly conserved cellular process of endocytosis by which extracellular fluid and nutrients are taken up into cells through large, heterogeneous vesicles known as macropinosomes. Growth factors such...