Takeshi Into
Overview
Explore the profile of Takeshi Into including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
5641
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Recent Articles
1.
Mori T, Kataoka H, Into T
J Oral Biosci
. 2023 Sep;
65(4):287-292.
PMID: 37659475
Objectives: Candidalysin (CL), a hydrophobic peptide toxin secreted by Candida albicans, is a key virulence factor that contributes to cytolysis, tissue damage, and immune activation. CL is thought to exert...
2.
Mori T, Kataoka H, Tanabe G, Into T
PLoS One
. 2022 Aug;
17(8):e0273663.
PMID: 36040970
Candidalysin, a peptide toxin produced specifically from hyphae of Candida albicans, plays a crucial role in C. albicans pathogenesis in the oral cavity and vagina. Synthetic peptides have been widely...
3.
Mori T, Kataoka H, Into T
J Oral Biosci
. 2021 May;
63(2):192-198.
PMID: 33933610
Objectives: Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by inflammatory lesions in the salivary and lacrimal glands, which are caused by distinct lymphocytic infiltrates. Female non-obese diabetic (NOD)...
4.
Kataoka H, Saeki A, Hasebe A, Shibata K, Into T
Food Sci Nutr
. 2021 Feb;
9(2):963-972.
PMID: 33598179
Toll-like receptors (TLRs) are important innate immune receptors that sometimes cause excessive inflammatory responses and a perpetuated inflammatory loop that can be involved in inflammatory and autoimmune diseases. TLR2 recognizes...
5.
Kataoka H, Mori T, Into T
J Med Microbiol
. 2021 Jan;
70(3).
PMID: 33439115
Food allergies (FAs) occur due to intestinal immune dysfunction elicited by dysbiotic conditions. It was previously determined by us that species propagate in the faeces of mice with FAs and...
6.
Ohno Y, Satoh K, Shitara A, Into T, Kashimata M
J Physiol
. 2020 Aug;
598(21):4907-4925.
PMID: 32780506
Key Points: Few reports have explored the possibility of involvement of non-inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA-sequencing analysis revealed that only four genes, including arginase 1,...
7.
Mizuno H, Takayama E, Satoh A, Into T, Adachi M, Ekuni D, et al.
Exp Ther Med
. 2020 Aug;
20(3):2822-2827.
PMID: 32765778
Salivary peroxidase and myeloperoxidase are known to display antibacterial activity against oral microbes, and previous indications have pointed to the possibility that horseradish peroxidase (HRP) adsorbs onto the membrane of...
8.
Saeki A, Tsuchiya K, Suda T, Into T, Hasebe A, Suzuki T, et al.
Immunology
. 2020 Jun;
161(2):114-122.
PMID: 32592165
Interleukin-1β (IL-1β) plays pivotal roles in controlling bacterial infections and is produced after the processing of pro-IL-1β by caspase-1, which is activated by the inflammasome. In addition, caspase-1 cleaves the...
9.
Inomata M, Horie T, Into T
Probiotics Antimicrob Proteins
. 2019 Nov;
12(1):64-72.
PMID: 31686299
The antimicrobial peptide LL-37 neutralizes the biological activity of lipopolysaccharide (LPS), while it upregulates the expression of several immune-related genes. We investigated the effect of LL-37 on gene regulation of...
10.
Horie T, Inomata M, Into T
J Pathog
. 2019 Jan;
2018:2068435.
PMID: 30687554
Subgingival bacteria are continually exposed to gingival crevicular fluids that are derived from serum, which contain various bactericidal agents. The periodontopathic bacterium has been demonstrated to possess a variety of...