Takayoshi Suganami
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Explore the profile of Takayoshi Suganami including associated specialties, affiliations and a list of published articles.
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117
Citations
4527
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Recent Articles
1.
Kohda H, Tanaka M, Shichino S, Arakawa S, Komori T, Ito A, et al.
Diabetes
. 2025 Mar;
PMID: 40063503
Recent evidence has shown that adipose tissue eventually develops fibrosis through complex cellular crosstalk. Although advances in single-cell transcriptomics have provided new insights into cell diversity during this process, little...
2.
Ito A, Suganami T
Front Immunol
. 2025 Feb;
15:1495853.
PMID: 39911578
Immune cells adapt their metabolism in response to their differentiation and activation status to meet the energy demands for an appropriate immune response. Recent studies have elucidated that during immune...
3.
Ishihara T, Kato K, Matsumoto K, Tanaka M, Hara A, Shiraki Y, et al.
Genes Cells
. 2024 Aug;
29(10):902-920.
PMID: 39136356
Identifying specific markers of adipose stem and progenitor cells (ASPCs) in vivo is crucial for understanding the biology of white adipose tissues (WAT). PDGFRα-positive perivascular stromal cells represent the best...
4.
Oya M, Miyasaka Y, Nakamura Y, Tanaka M, Suganami T, Mashimo T, et al.
Cell Metab
. 2024 Mar;
36(5):1044-1058.e10.
PMID: 38452767
Obesity is often associated with aging. However, the mechanism of age-related obesity is unknown. The melanocortin-4 receptor (MC4R) mediates leptin-melanocortin anti-obesity signaling in the hypothalamus. Here, we discovered that MC4R-bearing...
5.
Kato H, Iwashita K, Iwasa M, Kato S, Yamakage H, Suganami T, et al.
Cells
. 2024 Feb;
13(3.
PMID: 38334676
Type 2 diabetes mellitus (T2DM) is an epidemiological risk factor for dementia and has been implicated in multifactorial pathologies, including neuroinflammation. In the present study, we aimed to elucidate the...
6.
Itoh M, Tamura A, Kanai S, Tanaka M, Kanamori Y, Shirakawa I, et al.
J Exp Med
. 2023 Sep;
220(11).
PMID: 37725372
Accumulation of lipotoxic lipids, such as free cholesterol, induces hepatocyte death and subsequent inflammation and fibrosis in the pathogenesis of nonalcoholic steatohepatitis (NASH). However, the underlying mechanisms remain unclear. We...
7.
Iwasa M, Kato H, Iwashita K, Yamakage H, Kato S, Saito S, et al.
Nutrients
. 2023 Jun;
15(12).
PMID: 37375642
Type 2 diabetes mellitus is associated with an increased risk of dementia, potentially through multifactorial pathologies, including neuroinflammation. Therefore, there is a need to identify novel agents that can suppress...
8.
Shinoda Y, Tatsukawa H, Yonaga A, Wakita R, Takeuchi T, Tsuji T, et al.
Cell Death Dis
. 2023 Mar;
14(2):136.
PMID: 36864028
Macrophages are important components in modulating homeostatic and inflammatory responses and are generally categorized into two broad but distinct subsets: classical activated (M1) and alternatively activated (M2) depending on the...
9.
Inoue T, Fu B, Nishio M, Tanaka M, Kato H, Tanaka M, et al.
Nutrients
. 2023 Jan;
15(2).
PMID: 36678220
The molecular pathogenesis of nonalcoholic steatohepatitis (NASH) includes a complex interaction of metabolic stress and inflammatory stimuli. Considering the therapeutic goals of NASH, it is important to determine whether the...
10.
Ohue-Kitano R, Nonaka H, Nishida A, Masujima Y, Takahashi D, Ikeda T, et al.
JCI Insight
. 2022 Dec;
8(2).
PMID: 36480287
Medium-chain triglycerides (MCTs), which consist of medium-chain fatty acids (MCFAs), are unique forms of dietary fat with various health benefits. G protein-coupled 84 (GPR84) acts as a receptor for MCFAs...