Takashi Sasaya
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Explore the profile of Takashi Sasaya including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
48
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0
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Recent Articles
1.
Kato H, Tsukahara T, Murata K, Nishikata H, Mizue Y, Sasaya T, et al.
Cancer Immunol Immunother
. 2025 Mar;
74(4):133.
PMID: 40035876
The development of effective immunotherapies for solid tumors remains a significant challenge. In previous studies, we identified PVT1, a long non-coding RNA, with the peptide HF10 derived from PVT1, presented...
2.
Kikuchi N, Hatanaka S, Kubo T, Kamekura R, Kanda M, Kakuki T, et al.
Immunol Med
. 2025 Feb;
:1-7.
PMID: 39902902
Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory condition of unknown etiology characterized by lymphocytic infiltration, fibrosis, and infiltration of IgG4-positive plasma cells. It affects various organs, including the pancreas...
3.
Ogi K, Iwamoto T, Sasaya T, Nishiyama K, Tokura T, Sasaki T, et al.
Cancer Med
. 2024 Mar;
13(5):e6985.
PMID: 38491819
Background: Aberrant Notch signaling pathway has been related with the tumorigenesis in head and neck region, involving oral cavity. Here, we report the correlation between mutations in the Notch signaling...
4.
Miyamoto S, Nishikiori N, Sato T, Watanabe M, Umetsu A, Tsugeno Y, et al.
Cancers (Basel)
. 2023 Jun;
15(10).
PMID: 37345130
The objective of the current study was to elucidate the clinicopathological significance and appearance of in vitro three-dimension (3D) spheroid models of oral malignant tumors that were prepared from four...
5.
Miyamoto S, Hirohashi Y, Morita R, Miyazaki A, Ogi K, Kanaseki T, et al.
Cancer Sci
. 2023 Jun;
114(9):3496-3508.
PMID: 37344992
The mortality rate of oral cancer has not improved over the past three decades despite remarkable advances in cancer therapies. Oral cancers contain a subpopulation of cancer stem cells (CSCs)...
6.
Sasaya T, Kubo T, Murata K, Mizue Y, Sasaki K, Yanagawa J, et al.
Cancer Med
. 2022 Oct;
12(4):4605-4615.
PMID: 36200687
Immune checkpoint inhibitor-based cancer immunotherapy has provided an additional therapeutic option for oral squamous cell carcinoma (OSCC) with recurrence or distant metastases. However, further improvement of OSCC treatment is required...
7.
Koike K, Nishiyama K, Dehari H, Ogi K, Sasaki T, Shimizu S, et al.
Anticancer Res
. 2021 Sep;
41(9):4515-4522.
PMID: 34475077
Background/aim: The role of tumour-infiltrating CD45Ro T-cells in oral squamous cell carcinoma (OSCC) is unclear. This study aimed to evaluate prognostic biomarkers for OSCC. Patients And Methods: We determined the...
8.
Koike K, Dehari H, Ogi K, Shimizu S, Nishiyama K, Sonoda T, et al.
PLoS One
. 2020 Aug;
15(8):e0237465.
PMID: 32785290
Background: Tumor-infiltrating lymphocytes include tumor-reactive lymphocytes and regulatory T-cells. However, the prognostic value of tumor-infiltrating lymphocytes in oral squamous cell carcinoma (OSCC) remains unclear. Methods: We used immunohistochemistry to evaluate...
9.
Tsuchihashi K, Nakatsugawa M, Kobayashi J, Sasaya T, Morita R, Kubo T, et al.
Anticancer Res
. 2020 Jul;
40(8):4319-4326.
PMID: 32727759
Background/aim: The tumor microenvironment (TME) balances tumor growth and suppression through humoral factors and cell-cell interactions. In oral squamous cell carcinoma (OSCC), TMEs have been associated with prognosis of cancer...
10.
Koike K, Dehari H, Shimizu S, Nishiyama K, Sonoda T, Ogi K, et al.
Cancer Sci
. 2020 Mar;
111(5):1491-1499.
PMID: 32167621
Human leukocyte antigen (HLA) class Ⅰ molecules play a central role in anticancer immunity, but their prognostic value in oral squamous cell carcinoma (OSCC) remains unclear. We examined HLA class...