Takashi J Fuwa
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Explore the profile of Takashi J Fuwa including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
210
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0
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Recent Articles
1.
Abe E, Fuwa T, Hoshi K, Saito T, Murakami T, Miyajima M, et al.
Metabolites
. 2022 Jul;
12(7).
PMID: 35888718
Iron is an essential nutrient in the body. However, iron generates oxidative stress and hence needs to be bound to carrier proteins such as the glycoprotein transferrin (Tf) in body...
2.
Hoshi K, Ito H, Abe E, Fuwa T, Kanno M, Murakami Y, et al.
Metabolites
. 2021 Sep;
11(9).
PMID: 34564432
Glycosylation is a cell type-specific post-translational modification that can be used for biomarker identification in various diseases. Aim of this study is to explore glycan-biomarkers on transferrin (Tf) for Alzheimer's...
3.
Murakami Y, Matsumoto Y, Hoshi K, Ito H, Fuwa T, Yamaguchi Y, et al.
J Biochem
. 2018 Apr;
164(3):205-213.
PMID: 29701803
Idiopathic normal pressure hydrocephalus (iNPH) is a dementia-inducing disorder. Primary cause of iNPH is speculated to be a reduction of cerebrospinal fluid (CSF) absorption, which secondarily induces hydrocephalus, compression of...
4.
Kinoshita T, Sato C, Fuwa T, Nishihara S
Sci Rep
. 2017 Feb;
7:41455.
PMID: 28150729
T antigen, mucin-type core 1 O-glycan, is highly expressed in the embryonic central nervous system (CNS) and co-localizes with a Drosophila CNS marker, BP102 antigen. BP102 antigen and Derailed, an...
5.
Itoh K, Akimoto Y, Fuwa T, Sato C, Komatsu A, Nishihara S
Dev Biol
. 2016 Feb;
412(1):114-127.
PMID: 26896591
T antigen (Galβ1-3GalNAcα1-Ser/Thr), a core 1 mucin-type O-glycan structure, is synthesized by Drosophila core 1 β1,3-galactosyltrasferase 1 (dC1GalT1) and is expressed in various tissues. We previously reported that dC1GalT1 synthesizes...
6.
Takeuchi T, Nishiyama K, Saito S, Tamura M, Fuwa T, Nishihara S, et al.
Carbohydr Res
. 2015 May;
412:50-5.
PMID: 26025207
Galactoseβ1-4fucose (Galβ1-4Fuc) is a unique disaccharide unit that has been found only in the N-glycans of protostomia. We demonstrated that this unit has a role as an endogenous ligand for...
7.
Fuwa T, Kinoshita T, Nishida H, Nishihara S
Dev Biol
. 2015 Mar;
401(2):206-19.
PMID: 25779703
Hematopoietic stem cells (HSCs) are present in hematopoietic organs and differentiate into mature blood cells as required. Defective HSCs have been implicated in the human autoimmune disease Tn syndrome, which...
8.
Yamada K, Fuwa T, Ayukawa T, Tanaka T, Nakamura A, Wilkin M, et al.
Genes Cells
. 2011 Feb;
16(3):261-72.
PMID: 21299753
Cell signaling mediated by the Notch receptor (N) regulates many cell-fate decisions and is partly controlled by the endocytic trafficking of N. Drosophila deltex (dx) encodes an evolutionarily conserved regulator...
9.
Yoshida H, Fuwa T, Arima M, Hamamoto H, Sasaki N, Ichimiya T, et al.
Glycobiology
. 2008 Oct;
18(12):1094-104.
PMID: 18824562
T antigen (Galbeta1-3GalNAcalpha1-Ser/Thr), the well-known tumor-associated antigen, is a core 1 mucin-type O-glycan structure that is synthesized by core 1 beta1,3-galactosyltransferase (C1beta3GalT), which transfers Gal from UDP-Gal to Tn antigen...
10.
Sasaki N, Yoshida H, Fuwa T, Kinoshita-Toyoda A, Toyoda H, Hirabayashi Y, et al.
Biochem Biophys Res Commun
. 2007 Jan;
354(2):522-7.
PMID: 17239818
The GalNAcbeta1,4GlcNAc (LacdiNAc or LDN) structure is a more common structural feature in invertebrate glycoconjugates when compared with the Galbeta1,4GlcNAc structure. Recently, beta1,4-N-acetylgalactosaminyltransferase (beta4GalNAcT) was identified in some invertebrates including...