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Yasuhiro Hashimoto

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Articles 327
Citations 2894
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Recent Articles
1.
Tanegashima T, Shiota M, Terada N, Saito T, Yokomizo A, Kohei N, et al.
Int J Clin Oncol . 2024 Dec; 30(3):551-558. PMID: 39688742
Background: In Japan, since 2014, new treatments such as androgen receptor signaling inhibitors and cabazitaxel have become applicable for metastatic castration-resistant prostate cancer (mCRPC), leading to dramatic changes in treatment...
2.
Hashimoto Y, Yoshida Y, Yamada T, Yoshimatsu G, Yoshimura F, Hasegawa S
Cureus . 2024 Nov; 16(10):e71341. PMID: 39534818
Background Therapeutic drug monitoring (TDM) is an effective approach to improving the efficacy of drugs with a narrow therapeutic index and high toxicity. TDM-guided dosing of 5-fluorouracil (5-FU) has been...
3.
Uemura M, Kikukawa H, Hashimoto Y, Uemura H, Mizokami A, Kato M, et al.
Cancer Med . 2024 Nov; 13(21):e70029. PMID: 39527466
Background: In the global ARASENS study (NCT02799602), darolutamide plus androgen-deprivation therapy (ADT) and docetaxel significantly reduced risk of death by 32.5% versus placebo plus ADT and docetaxel (hazard ratio [HR]...
4.
Hashimoto Y, Takahashi H, Nagaura H, Yoshitake S, Nakata H
PLoS One . 2024 Aug; 19(8):e0309328. PMID: 39163361
This study examines baseball players' recognition framework of out, ball, and strike counts in baseball games and clarifies the differences in psychological perspectives between batters and pitchers. The participants were...
5.
Imada K, Miyakawa Y, Ichikawa S, Uchiyama H, Ueda Y, Hashimoto Y, et al.
Thromb J . 2024 Aug; 22(1):72. PMID: 39095866
Background: A recent Phase 2/3 study in Japanese patients showed that caplacizumab was effective in treating immune-mediated thrombotic thrombocytopenic purpura (iTTP), with a low rate of iTTP recurrence. ADAMTS13 activity...
6.
Fujita N, Okamoto T, Yamamoto H, Yoneyama T, Hashimoto Y, Mikami T, et al.
Sci Rep . 2024 Jun; 14(1):13433. PMID: 38862562
In addition to testosterone, various endocrine hormones, such as dehydroepiandrosterone sulfate (DHEA-S) and estradiol, may be involved in erectile function. However, the role of these sex hormones in the erectile...
7.
Fujita N, Momota M, Soma O, Noro D, Mikami J, Miura Y, et al.
World J Urol . 2024 May; 42(1):301. PMID: 38717511
Purpose: To evaluate the impact of severe acute kidney injury (AKI) on short-term mortality in patients with urosepsis. Methods: This prospective cohort study evaluated 207 patients with urosepsis. AKI was...
8.
Fujita N, Iwane T, Tamura Y, Okamoto T, Yamamoto H, Hatakeyama S, et al.
Int J Urol . 2024 May; 31(8):869-875. PMID: 38695270
Objectives: Several systematic reviews and meta-analyses have reported positive relationships between erectile dysfunction (ED) and periodontal disease. However, no study has evaluated the relationships of occlusal support status and the...
9.
Fujita N, Hatakeyama S, Tabata R, Okita K, Kido K, Hamano I, et al.
Prostate Int . 2024 Mar; 12(1):46-51. PMID: 38523900
Background: The benefits of novel androgen receptor axis-targeted agents (ARATs) on oncological outcomes in patients with non-metastatic castration-resistant prostate cancer (nmCRPC) in real-world settings are unclear. Methods: This multi-institutional retrospective...
10.
Murakami T, Abe M, Tiksnadi A, Nemoto A, Futamura M, Yamakuni R, et al.
Clin Neurophysiol . 2024 Jan; 158:170-179. PMID: 38219406
Objective: Amyloid-beta (Aβ) and tau accumulations impair long-term potentiation (LTP) induction in animal hippocampi. We investigated relationships between motor-cortical plasticity and biomarkers for Alzheimer's disease (AD) diagnosis in subjects with...