Takashi Hiroyama
Overview
Explore the profile of Takashi Hiroyama including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
710
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0
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Recent Articles
1.
Seyama Y, Sudo K, Hirose S, Hamano Y, Yamada T, Hiroyama T, et al.
Hum Cell
. 2023 Aug;
36(6):2074-2086.
PMID: 37610679
The identification and development of therapeutic targets in cancer stem cells that lead to tumor development, recurrence, metastasis, and drug resistance is an important goal in cancer research. The hepatocellular...
2.
Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, et al.
Nat Commun
. 2023 Jan;
14(1):23.
PMID: 36635268
Sickle cell disease (SCD) is a heritable disorder caused by β-globin gene mutations. Induction of fetal γ-globin is an established therapeutic strategy. Recently, epigenetic modulators, including G9a inhibitors, have been...
3.
Sato Y, Yamada T, Hiroyama T, Sudo K, Hasegawa N, Hyodo I, et al.
Cancer Sci
. 2019 Feb;
110(5):1644-1652.
PMID: 30784169
Cancer tissues contain small populations of highly tumorigenic cells termed cancer stem cells (CSCs). Immortalized cell lines containing CSCs are valuable and powerful experimental tools for research into the characteristics...
4.
Shibagaki S, Tahara-Hanaoka S, Hiroyama T, Nakamura Y, Shibuya A
Int Immunol
. 2017 Apr;
29(5):235-242.
PMID: 28431112
Mast cells (MCs) play pivotal roles in allergic reactions and the host defense against microbial infection through the IgE-dependent and IgE-independent signaling pathways. MC lines that can be analyzed both...
5.
Kanemaru K, Noguchi E, Tokunaga T, Nagai K, Hiroyama T, Nakamura Y, et al.
PLoS One
. 2015 Dec;
10(12):e0144436.
PMID: 26659448
Mast cell (MC) activation contributes considerably to immune responses, such as host protection and allergy. Cell surface immunoreceptors expressed on MCs play an important role in MC activation. Although various...
6.
Kurita R, Suda N, Sudo K, Miharada K, Hiroyama T, Miyoshi H, et al.
PLoS One
. 2013 Mar;
8(3):e59890.
PMID: 23533656
Transfusion of red blood cells (RBCs) is a standard and indispensable therapy in current clinical practice. In vitro production of RBCs offers a potential means to overcome a shortage of...
7.
Danjoh I, Sone H, Shirota R, Hiroyama T, Nakamura Y
In Vitro Cell Dev Biol Anim
. 2012 Jul;
48(7):393-402.
PMID: 22806969
B lymphoblastoid cell lines (B-LCLs) are generally established from B lymphocytes by infection with Epstein-Barr virus (EBV). As their genomic structure is stable in culture, B-LCLs are a valuable resource...
8.
Hiroyama T, Miharada K, Kurita R, Nakamura Y
Stem Cells Int
. 2011 Jul;
2011:195780.
PMID: 21785608
The supply of transfusable red blood cells (RBCs) is not sufficient in many countries. If transfusable RBCs could be produced abundantly from certain resources, it would be very useful. Our...
9.
Danjoh I, Saijo K, Hiroyama T, Nakamura Y
Genome Biol Evol
. 2011 Mar;
3:272-83.
PMID: 21383383
The Sonoda-Tajima Cell Collection includes cell samples obtained from a range of ethnic minority groups across the world but in particular from South America. The collection is made all the...
10.
Nakamura Y, Hiroyama T, Miharada K, Kurita R
Int J Hematol
. 2010 Dec;
93(1):5-9.
PMID: 21184289
The supply of transfusable red blood cells (RBCs) is not sufficient in many countries. If immortalized erythroid progenitor cell lines able to produce transfusable RBCs in vitro were established, they...