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Takao Hamakubo

Explore the profile of Takao Hamakubo including associated specialties, affiliations and a list of published articles. Areas
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Articles 189
Citations 5253
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Recent Articles
1.
Komatsu N, Kosai A, Kuroda M, Hamakubo T, Abe T
Biomedicines . 2024 May; 12(5). PMID: 38790935
Background: Photodynamic therapy (PDT) is a cancer-targeted treatment that uses a photosensitizer (PS) and irradiation of a specific wavelength to exert cytotoxic effects. To enhance the antitumor effect against head...
2.
Delaney S, Keinanen O, Lam D, Wolfe A, Hamakubo T, Zeglis B
Eur J Nucl Med Mol Imaging . 2024 Apr; 51(9):2547-2557. PMID: 38625402
Purpose: Cadherin-17 (CDH17) is a calcium-dependent cell adhesion protein that is overexpressed in several adenocarcinomas, including gastric, colorectal, and pancreatic adenocarcinoma. High levels of CDH17 have been linked to metastatic...
3.
Jaunet-Lahary T, Shimamura T, Hayashi M, Nomura N, Hirasawa K, Shimizu T, et al.
Nat Commun . 2023 Sep; 14(1):6053. PMID: 37770479
No abstract available.
4.
Abe Y, Kofman E, Almeida M, Ouyang Z, Ponte F, Mueller J, et al.
Mol Cell . 2023 Sep; 83(19):3421-3437.e11. PMID: 37751740
The nuclear receptor co-repressor (NCoR) complex mediates transcriptional repression dependent on histone deacetylation by histone deacetylase 3 (HDAC3) as a component of the complex. Unexpectedly, we found that signaling by...
5.
Fujiwara K, Tsuji A, Sudo H, Sugyo A, Hamakubo T, Higashi T
Nucl Med Commun . 2023 Sep; 45(1):68-76. PMID: 37728607
Background: Small cell lung cancer (SCLC) has a poor prognosis, and Roundabout homolog 1 (ROBO1) is frequently expressed in SCLC. ROBO1-targeted radioimmunotherapy (RIT) previously showed tumor shrinkage, but regrowth with...
6.
Yasuda D, Hamano F, Masuda K, Dahlstrom M, Kobayashi D, Sato N, et al.
Eur J Pharmacol . 2023 Jul; 954:175893. PMID: 37392830
GPR82 is an orphan G protein-coupled receptor (GPCR) that has been implicated in lipid storage in mouse adipocytes. However, the intracellular signaling as well as the specific ligands of GPR82...
7.
Jaunet-Lahary T, Shimamura T, Hayashi M, Nomura N, Hirasawa K, Shimizu T, et al.
Nat Commun . 2023 Apr; 14(1):1730. PMID: 37012268
An oxalate-degrading bacterium in the gut microbiota absorbs food-derived oxalate to use this as a carbon and energy source, thereby reducing the risk of kidney stone formation in host animals....
8.
Sonokawa T, Obi N, Usuda J, Sudo Y, Hamakubo T
Thorac Cancer . 2023 Jan; 14(7):645-653. PMID: 36655546
Background: Photodynamic therapy (PDT) is a cancer-targeted treatment that uses a photosensitizer (PS) and laser irradiation. The effectiveness of current PDT using red light for advanced cancers is limited, because...
9.
Horiuchi K, Kawamura T, Hamakubo T
J Biol Chem . 2021 Sep; 297(5):101248. PMID: 34582888
Wilms' tumor 1-associating protein (WTAP) is a core component of the N6-methyladenosine (m6A)-methyltransferase complex, along with VIRMA, CBLL1, ZC3H13 (KIAA0853), RBM15/15B, and METTL3/14, which generate m6A, a key RNA modification...
10.
Kitoh T, Ohara T, Muto T, Okumura A, Baba R, Koizumi Y, et al.
Front Immunol . 2021 Apr; 12:624802. PMID: 33912155
Kawasaki disease (KD) is a febrile disease of childhood characterized by systemic vasculitis that can lead to coronary artery lesions (CAL). This was a prospective cohort study to determine the...