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Takanobu Shimada

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Articles 10
Citations 62
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Recent Articles
1.
Matsumoto T, Yamamura S, Ikoma T, Kurioka Y, Doi K, Yasuda T, et al.
Clin Med Insights Oncol . 2022 Nov; 16:11795549221137135. PMID: 36408335
Background: A trial with trifluridine/tipiracil (FTD/TPI) versus placebo in patients with heavily pretreated metastatic gastric cancer showed that FTD/TPI is effective with manageable toxicity in these patients. However, real-world data...
2.
Ikoma T, Shimokawa M, Matsumoto T, Boku S, Yasuda T, Shibata N, et al.
Cancer Immunol Immunother . 2022 Aug; 72(2):427-435. PMID: 35927359
Background: In Japan, nivolumab administration is the standard treatment for patients with unresectable advanced or recurrent esophageal squamous cell carcinoma (ESCC) who are refractory or intolerant to fluoropyrimidines and platinum-based...
3.
Matsumoto T, Yamamura S, Ikoma T, Kurioka Y, Doi K, Boku S, et al.
J Clin Med . 2022 Apr; 11(8). PMID: 35456340
Trastuzumab deruxtecan (T-DXd) has shown promising efficacy against positive advanced gastric cancer (AGC). However, data on its real-world efficacy in AGC patients are insufficient, and the predictive marker of T-DXd...
4.
Okada T, Fukuhara T, Tanaka S, Taguchi M, Arai T, Senshu H, et al.
Nature . 2020 Mar; 579(7800):518-522. PMID: 32214245
Carbonaceous (C-type) asteroids are relics of the early Solar System that have preserved primitive materials since their formation approximately 4.6 billion years ago. They are probably analogues of carbonaceous chondrites...
5.
Goto F, Arai M, Kitamura M, Otomo T, Nagai R, Minami S, et al.
Iran J Otorhinolaryngol . 2016 Jun; 28(85):149-52. PMID: 27280102
Introduction: The aim of this case report was to investigate the relationship between sleep disorders and audio vestibular symptoms. Case Report: A case of undiagnosed sleep disorder, presenting as a...
6.
Kataoka T, Kiyota N, Shimada T, Funakoshi Y, Chayahara N, Toyoda M, et al.
Auris Nasus Larynx . 2016 Mar; 43(6):677-84. PMID: 26992271
Objective: Radiation-induced mucositis (RIM) in chemoradiotherapy (CRT) for head and neck cancer (HNC) causes severe pain and worsens CRT compliance, QOL and outcome. Following retrospective reports, we conducted a randomized...
7.
Funakoshi Y, Fujiwara Y, Kiyota N, Mukohara T, Shimada T, Toyoda M, et al.
Cancer Chemother Pharmacol . 2016 Jan; 77(2):281-8. PMID: 26791871
Purpose: Creatinine clearance (Ccr) is used as a marker of renal function in cancer chemotherapy, but it is not correlated with glomerular filtration rate (GFR) after high-dose cisplatin treatment. In...
8.
Fujiwara Y, Toyoda M, Chayahara N, Kiyota N, Shimada T, Imamura Y, et al.
PLoS One . 2014 Aug; 9(8):e104215. PMID: 25121773
Purpose: Oxycodone is a µ-opioid receptor agonist widely used in the treatment of cancer pain. The predominant metabolic pathway of oxycodone is CYP3A4-mediated N-demethylation to noroxycodone, while a minor proportion...
9.
Funakoshi Y, Fujiwara Y, Kiyota N, Mukohara T, Shimada T, Toyoda M, et al.
Jpn J Clin Oncol . 2013 Jan; 43(3):271-7. PMID: 23329851
Background: Assessment of renal function is important for safe cancer chemotherapy, and eligibility criteria for clinical trials often include creatinine clearance. However, creatinine clearance overestimates glomerular filtration rate, and various...
10.
Okamura A, Yakushijin K, Inui Y, Funakoshi Y, Kawamori Y, Shimada T, et al.
Int J Hematol . 2011 Apr; 93(6):765-770. PMID: 21512728
In allogeneic hematopoietic stem cell transplantation (allo-SCT), most physicians in Japan utilize granulocyte colony-stimulating factor (G-CSF) at a high dose (HD) of 300 μg/m(2) per day for filgrastim to promote...