Takahisa Matsuzaki
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Explore the profile of Takahisa Matsuzaki including associated specialties, affiliations and a list of published articles.
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22
Citations
295
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Recent Articles
1.
Matsuzaki T, Fujii M, Noro H, Togo S, Watanabe M, Suganuma M, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(50):e2412914121.
PMID: 39636859
We developed an advanced optical microscope for the simultaneous visualization of membrane fluidity and morphology to define cell adhesion signatures. This microscope combines ratiometric spectral imaging of membrane fluidity and...
2.
Mizuno M, Maeda Y, Sanami S, Matsuzaki T, Yoshikawa H, Ozeki N, et al.
iScience
. 2024 Feb;
27(3):109170.
PMID: 38405610
The inherent variability in cell culture techniques hinders their reproducibility. To address this issue, we introduce a comprehensive cell observation device. This new approach enhances the features of existing home-use...
3.
Horikiri M, Taniguchi M, Yoshikawa H, Okumura R, Matsuzaki T
Methods Mol Biol
. 2024 Feb;
2763:403-414.
PMID: 38347430
Mucus is part of the innate immune system that defends the mucosa against microbiota and other infectious threats. The mechanical characteristics of mucus, such as viscosity, elasticity, and lubricity, are...
4.
Matsuzaki T, Kawamura R, Yamamoto A, Takahashi H, Fujii M, Togo S, et al.
J Phys Chem Lett
. 2024 Jan;
15(4):1097-1104.
PMID: 38262433
Interference reflection microscopy (IRM) is a powerful, label-free technique to visualize the surface structure of biospecimens. However, stray light outside a focal plane obscures the surface fine structures beyond the...
5.
Matsuzaki T, Kawano Y, Horikiri M, Shimokawa Y, Yamazaki T, Okuma N, et al.
STAR Protoc
. 2023 Jul;
4(3):102471.
PMID: 37515762
Synthetic protocols providing mechanical patterns to culture substrate are essential to control the self-condensation of cells for organoid engineering. Here, we present a protocol for preparing hydrogels with mechanical patterns....
6.
Taniguchi M, Okumura R, Matsuzaki T, Nakatani A, Sakaki K, Okamoto S, et al.
Mucosal Immunol
. 2023 Jun;
16(5):624-641.
PMID: 37385587
In the intestine, mucin 2 (Muc2) forms a network structure and prevents bacterial invasion. Glycans are indispensable for Muc2 barrier function. Among various glycosylation patterns of Muc2, sialylation inhibits bacteria-dependent...
7.
Kitagawa K, Okuma N, Yoshinaga M, Takemae H, Sato F, Sato S, et al.
Bioconjug Chem
. 2023 Feb;
PMID: 36763006
Bio-orthogonal ligations that crosslink living cells with a substrate or other cells require high stability and rapid kinetics to maintain the nature of target cells. In this study, we report...
8.
Matsuzaki T, Shimokawa Y, Koike H, Kimura M, Kawano Y, Okuma N, et al.
iScience
. 2022 Nov;
25(10):105109.
PMID: 36317160
Spatially controlled self-organization represents a major challenge for organoid engineering. We have developed a mechanically patterned hydrogel for controlling self-condensation process to generate multi-cellular organoids. We first found that local...
9.
Matsuzaki T, Terutsuki D, Sato S, Ikarashi K, Sato K, Mitsuno H, et al.
J Phys Chem Lett
. 2022 Oct;
13(40):9494-9500.
PMID: 36201238
Cell-coupled field-effect transistor (FET) biosensors have attracted considerable attention because of their high sensitivity to biomolecules. The use of insect cells (Sf21) as a core sensor element is advantageous due...
10.
Mizuno M, Matsuzaki T, Ozeki N, Katano H, Koga H, Takebe T, et al.
Stem Cell Res Ther
. 2022 May;
13(1):177.
PMID: 35505370
Objectives: Synovial mesenchymal stem cells (MSCs) have high freeze-thaw tolerance, whereas human umbilical vein endothelial cells (HUVECs) have low freezing tolerance. The differences in cell type-specific freeze-thaw tolerance and the...