Takaaki Goto
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Explore the profile of Takaaki Goto including associated specialties, affiliations and a list of published articles.
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59
Citations
312
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Recent Articles
11.
Suzuki K, Okumura Y, Kita Y, Oi Y, Yamashita Y, Goto T, et al.
Neuroreport
. 2017 Jun;
28(13):828-832.
PMID: 28628557
Near-infrared spectroscopy studies in children with attention deficit hyperactivity disorder (ADHD) have shown excessive prefrontal activity responsible for coping with interference. However, it is possible that the previous results were...
12.
Goto T, Sato K, Sone H, Koganezawa M, Ito H, Yamamoto D
J Neurogenet
. 2015 Nov;
29(4):169-73.
PMID: 26577029
In the pupal stage, the fly body undergoes extensive metamorphic remodeling, in which programmed cell death plays a critical role. We studied two of the constituent processes in this remodeling,...
13.
Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, et al.
Biol Reprod
. 2015 Sep;
93(4):90.
PMID: 26333992
Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is a type of membrane receptor with a seven-transmembrane structure. LGR4 is homologous to gonadotropin receptors, such as follicle-stimulating hormone receptor (Fshr) and...
14.
Goto T, Kita Y, Suzuki K, Koike T, Inagaki M
Front Hum Neurosci
. 2015 Aug;
9:417.
PMID: 26236223
Phonological awareness is essential for reading, and is common to all language systems, including alphabetic languages and Japanese. This cognitive factor develops during childhood, and is thought to be associated...
15.
Takahashi R, Goto T, Oe T, Lee S
Chem Biol Interact
. 2015 Jun;
239:87-99.
PMID: 26111765
Polyunsaturated fatty acids are highly susceptible to oxidation induced by reactive oxygen species and enzymes, leading to the formation of lipid hydroperoxides. The linoleic acid (LA)-derived hydroperoxide, 13-hydroperoxyoctadecadienoic acid (HPODE)...
16.
Kume K, Sakai N, Goto T
Endoscopy
. 2015 Apr;
47(9):815-9.
PMID: 25910062
Background And Aims: The next generation of flexible endoscopy platforms such as The Master and Slave Transluminal Endoscopic Robot (MASTER) is primarily for remote control manipulation of forceps, but manipulation...
17.
Lee S, Kyung H, Yokota R, Goto T, Oe T
Chem Res Toxicol
. 2014 Nov;
28(1):59-70.
PMID: 25422125
The hydroxyl radical-mediated oxidation of peptides and proteins constitutes a large group of post-translational modifications that can result in structural and functional changes. These oxidations can lead to hydroxylation, sulfoxidation,...
18.
Lee S, Kyung H, Yokota R, Goto T, Oe T
Chem Res Toxicol
. 2014 Feb;
27(4):637-48.
PMID: 24568234
We have previously reported that N-terminal α-ketoamide peptides can be formed through 4-oxo-2(E)-nonenal (ONE)-derived oxidative decarboxylation of aspartic acid (Asp), which converts angiotensin (Ang) II (DRVYIHPF) to pyruvamide-Ang II (Ang...
19.
Osaki F, Goto T, Lee S, Oe T
Anal Biochem
. 2013 Dec;
449:59-67.
PMID: 24361714
Metabolic activation of drugs frequently generates electrophilic products that may undergo covalent binding to biological macromolecules, such as proteins and DNA. The resulting covalent adducts are of considerable concern in...
20.
Kajita R, Goto T, Lee S, Oe T
Chem Res Toxicol
. 2013 Dec;
26(12):1926-36.
PMID: 24299224
Various kinds of aldehyde-mediated chemical modifications of proteins have been identified as being exclusively covalent. We report a unique noncovalent modification: the aldehyde-mediated epimerization of the N-terminal amino acid. Epimerization...