Tahsin N Khan
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Explore the profile of Tahsin N Khan including associated specialties, affiliations and a list of published articles.
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10
Citations
412
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Recent Articles
1.
Pajarinen J, Lin T, Nabeshima A, Sato T, Gibon E, Jamsen E, et al.
J Biomed Mater Res A
. 2020 Dec;
109(8):1512-1520.
PMID: 33340244
Periprosthetic osteolysis remains as a major complication of total joint replacement surgery. Modulation of macrophage polarization with interleukin-4 (IL-4) has emerged as an effective means to limit wear particle-induced osteolysis....
2.
Osborn J, Hobbs S, Mooster J, Khan T, Kilgore A, Harbour J, et al.
PLoS Pathog
. 2019 Mar;
15(3):e1007633.
PMID: 30875408
Memory CD8+ T cells in the circulation rapidly infiltrate non-lymphoid tissues following infection and provide protective immunity in an antigen-specific manner. However, the subsequent fate of memory CD8+ T cells...
3.
Lin T, Pajarinen J, Kohno Y, Maruyama M, Romero-Lopez M, Huang J, et al.
Cytotherapy
. 2018 Aug;
20(8):1028-1036.
PMID: 30077567
Background: Mesenchymal stromal cell (MSC)-based therapy has great potential to modulate chronic inflammation and enhance tissue regeneration. Crosstalk between MSC-lineage cells and polarized macrophages is critical for bone formation and...
4.
Khan T, Mooster J, Kilgore A, Osborn J, Nolz J
J Exp Med
. 2016 May;
213(6):951-66.
PMID: 27217536
Tissue-resident memory (Trm) CD8(+) T cells are functionally distinct from their circulating counterparts and are potent mediators of host protection against reinfection. Whether local recognition of antigen in nonlymphoid tissues...
5.
Soni C, Domeier P, Wong E, Shwetank , Khan T, Elias M, et al.
J Autoimmun
. 2015 Jul;
63:31-46.
PMID: 26162758
The inhibitory IgG Fc receptor (FcγRIIB) deficiency and 129 strain-derived signaling lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus phenotype in FcγRIIB-deficient mice generated using 129 ES...
6.
Wong E, Soni C, Chan A, Domeier P, Shwetank , Abraham T, et al.
J Immunol
. 2015 Mar;
194(9):4130-43.
PMID: 25801429
Signaling lymphocyte activation molecules (SLAMs) play an integral role in immune regulation. Polymorphisms in the SLAM family receptors are implicated in human and mouse model of lupus disease. The lupus-associated,...
7.
Soni C, Wong E, Domeier P, Khan T, Satoh T, Akira S, et al.
J Immunol
. 2014 Sep;
193(9):4400-14.
PMID: 25252960
Spontaneous germinal center (Spt-GC) B cells and follicular helper T cells generate high-affinity autoantibodies that are involved in the development of systemic lupus erythematosus. TLRs play a pivotal role in...
8.
Khan T, Wong E, Soni C, Rahman Z
J Immunol
. 2013 Jan;
190(4):1433-46.
PMID: 23319738
Mer receptor tyrosine kinase is a member of the Tyro-3/Axl/Mer (TAM) subfamily of receptor tyrosine kinases, and its expression on phagocytes facilitates their clearance of apoptotic cells (ACs). Mer expression...
9.
Wong E, Khan T, Mohan C, Rahman Z
J Immunol
. 2012 Nov;
189(12):5667-81.
PMID: 23144494
C57BL/6 (B6) mice carrying the Sle1b sublocus (named B6.Sle1b), which harbors the lupus-associated NZM2410/NZW SLAM family genes, produce antinuclear Abs (ANAs). However, the role and mechanism(s) involved in the alteration...
10.
Rahman Z, Shao W, Khan T, Zhen Y, Cohen P
J Immunol
. 2010 Oct;
185(10):5859-68.
PMID: 20952679
Germinal centers (GCs) are specialized microenvironments that generate high-affinity Ab-forming cells (AFCs) and memory B cells. Many B cells undergo apoptosis during B cell clonal selection in GCs. Although the...