Tae Hyeon An
Overview
Explore the profile of Tae Hyeon An including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
94
Followers
0
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Recent Articles
1.
Park H, Choi J, Kim H, Yang D, An T, Lee E, et al.
Front Mol Biosci
. 2024 Nov;
11:1511947.
PMID: 39529685
[This corrects the article DOI: 10.3389/fmolb.2023.1221669.].
2.
Kim S, Park S, Kim J, Hong S, Cho S, Lim S, et al.
Exp Mol Med
. 2024 Nov;
56(11):2395-2408.
PMID: 39482535
Mitochondrial dysfunction induced by mitochondrial DNA (mtDNA) mutations has been implicated in various human diseases. A comprehensive analysis of mitochondrial genetic disorders requires suitable animal models for human disease studies....
3.
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA
Cho S, Lim K, Hong S, Lee J, Kim A, Lim C, et al.
Cell
. 2024 Jan;
187(1):95-109.e26.
PMID: 38181745
DddA-derived cytosine base editors (DdCBEs) and transcription activator-like effector (TALE)-linked deaminases (TALEDs) catalyze targeted base editing of mitochondrial DNA (mtDNA) in eukaryotic cells, a method useful for modeling of mitochondrial...
4.
Park H, Choi J, Kim H, Yang D, An T, Lee E, et al.
Front Mol Biosci
. 2023 Aug;
10:1221669.
PMID: 37635938
Nonalcoholic fatty liver disease (NAFLD) is a progressive liver disease that can progress to nonalcoholic steatohepatitis (NASH), NASH-related cirrhosis, and hepatocellular carcinoma (HCC). NAFLD ranges from simple steatosis (or nonalcoholic...
5.
Lee D, An T, Kim H, Jung E, Kim G, Oh S, et al.
Diabetologia
. 2023 Feb;
66(5):931-954.
PMID: 36759348
Aims/hypothesis: Non-alcoholic fatty liver disease (NAFLD) associated with type 2 diabetes may more easily progress towards severe forms of non-alcoholic steatohepatitis (NASH) and cirrhosis. Although the Wnt effector transcription factor...
6.
Jang J, Lee J, Cho M, Hwang B, Kwon M, Kim D, et al.
Exp Mol Med
. 2022 Aug;
54(8):1250-1261.
PMID: 36028759
Obesity is a growing global epidemic that can cause serious adverse health consequences, including insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD). Obesity development can be attributed to energy...
7.
Kim H, Lee D, An T, Park H, Kim W, Bae K, et al.
Int J Mol Sci
. 2021 Apr;
22(9).
PMID: 33925827
Liver disease is the spectrum of liver damage ranging from simple steatosis called as nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically, NAFLD and type 2 diabetes coexist....
8.
Kim H, Lee D, An T, Park T, Lee E, Han B, et al.
Biomedicines
. 2021 Jan;
9(1).
PMID: 33435535
Increased hepatic gluconeogenesis is one of the main contributors to the development of type 2 diabetes. Recently, it has been reported that growth arrest and DNA damage-inducible 45 beta (GADD45β)...
9.
Byun S, An T, Son M, Lee D, Kang H, Lee E, et al.
Mol Cells
. 2017 Sep;
40(9):667-676.
PMID: 28927261
Abnormal differentiation of muscle is closely associated with aging (sarcopenia) and diseases such as cancer and type II diabetes. Thus, understanding the mechanisms that regulate muscle differentiation will be useful...